37 items found

Types: other Groups: Open Access Tags: Molecular Biology

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    The outcome of structural heart defects diagnosed in the first trimester of p...

    Purpose: We present the results of a detailed protocol of fetal heart examination in the first trimester, in a fetal medicine unit in Romania. Methods: Since October 2009, in...
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    Saliva cortisol in relation to aircraft noise exposure: pooled-analysis resul...

    Abstract Background Many studies have demonstrated adverse effects of exposure to aircraft noise on health. Possible biological pathways for these effects include hormonal...
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    Fluid management of the neurological patient: A concise review

    textabstractMaintenance fluids in critically ill brain-injured patients are part of routine critical care. Both the amounts of fluid volumes infused and the type and tonicity of...
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    Cord blood DNA methylation reflects cord blood C-reactive protein levels but ...

    Abstract Background Prenatal inflammation has been proposed as an important mediating factor in several adverse pregnancy outcomes. C-reactive protein (CRP) is an inflammatory...
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    A global sensitivity analysis approach for morphogenesis models

    Abstract Background Morphogenesis is a developmental process in which cells organize into shapes and patterns. Complex, non-linear and multi-factorial models with images as...
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    Comparative and selection sweep analysis of CNV was associated to litter size...

    This study aims to identify the relative Copy number variation (CNV) associated with the litter size of Dazu black goats based on the unpublished CNV analytical results of our...
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    Specificity versus redundancy in the RAP2.4 transcription factor family of Ar...

    Abstract Background The Arabidopsis ERFIb / RAP2.4 transcription factor family consists of eight members with highly conserved DNA binding domains. Selected members have been...
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    Benefits and harm of systemic steroids for short- And long-term use in rhinit...

    Abstract Because of the inflammatory mechanisms of most chronic upper airway diseases such as rhinitis and chronic rhinosinusitis, systemic steroids have been used for their...
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    Predictors of delayed culture conversion among Ugandan patients

    Abstract Background Estimates of month-2 culture conversion, a proxy indicator of tuberculosis (TB) treatment efficacy in phase-2 trials can vary by culture-type and...
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    Associations of tobacco smoking with body mass distribution; a population-bas...

    Abstract Background Studies indicate an effect of smoking toward abdominal obesity, but few assess hip and waist circumferences (HC and WC) independently. The present study...
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    Development of a framework with tools to support the selection and implementa...

    Abstract Background Patient reported outcomes (PROs) provide information on a patient’s health status coming directly from the patient. Measuring PROs with patient reported...
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    PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma

    Abstract Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead...
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    Role of goblet cell protein CLCA1 in murine DSS colitis

    Abstract Background The secreted goblet cell protein CLCA1 (chloride channel regulator, calcium-activated-1) is, in addition to its established role in epithelial chloride...
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    Abdominal obesity increases metabolic risk factors in non-obese adults: a Hun...

    Abstract Background The prevalence of abdominal obesity is increasing worldwide. Adults with abdominal obesity have been reported to have increased risk of cardiometabolic...
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    A combined epigenome- and transcriptome-wide association study of the oral ma...

    Abstract Background The oral mucosa has an important role in maintaining barrier integrity at the gateway to the gastrointestinal and respiratory tracts. Smoking is a strong...
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    Evaluation of whole exome sequencing as an alternative to BeadChip and whole ...

    Abstract Background Understanding the underlying genetic structure of human populations is of fundamental interest to both biological and social sciences. Advances in...
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    Reduced endogenous secretory RAGE in blood and bronchoalveolar lavage fluid i...

    Abstract Background The endogenous secretory receptor for advanced glycation end products (esRAGE) is a soluble isoform produced by alternative splicing of the RAGE gene. The...
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    Omic personality: implications of stable transcript and methylation profiles ...

    Abstract Background Personalized medicine is predicated on the notion that individual biochemical and genomic profiles are...
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    A critical review of representation in the development of global oncology cur...

    Abstract Background Global curricular homogenization is purported to have a multitude of benefits. However, homogenization, as typically practiced has been found to promote...
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    Cold seawater induces early sexual developmental stages in the BPG axis of Eu...

    Abstract Background The impossibility of closing the life cycle of the European eel (Anguilla anguilla) in captivity troubles the future of this critically endangered species....