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r37980778c78--ee1ddfb71c5b00bb33f52089b864609b
ImportanceEpigenetic modifications of the genome, such as DNA methylation and histone modifications, have been reported to play a role in neurodegenerative diseases (ND) such as... -
r37980778c78--64c46fcf2abd434b500175d0e3919c54
Alzheimer’s disease (AD) is a neurodegenerative disorder that has a higher prevalence and incidence in people older than 60 years. The need for improved AD therapies is unmet as... -
r37980778c78--ea415cc55faedaf9d4f8506e4027b26a
Genetic sexing results for the ancient huanchaquito las llamas samples and mitochondrial haplogroups. -
r37980778c78--d0850284f6e377c80587f5ff34b89303
A, B, Quantitative RT-PCR result of IDE in TR-AST cells and rat primary astrocytes. TR-AST cells and primary astrocytes were treated with hydrogen peroxide in indicated... -
Hazard ratios of use of sedative-hypnotics prescribed in insomnia patients on...
Hazard ratios of use of sedative-hypnotics prescribed in insomnia patients on Alzheimer's dementia by time-dependent Cox regression model classified by dose, types and... -
Calculated hazard ratios of dementia (Alzheimer’s and vascular) in the AS and...
Calculated hazard ratios of dementia (Alzheimer’s and vascular) in the AS and control groups. -
r37980778c78--2fdc6848b2f1333ee64a1cc8e6190e84
The study aims to clarify the mechanism in patients with neurally mediated syncope (NMS), focusing on the adenylate cyclase (AC) activity level in lymphocytes. This study... -
Demographics and clinical characteristics.
Values are mean ± standard deviation unless otherwise noted. Categorical data are compared by chi-square tests, two tailed; all other p values are by Student's t test, two tailed. -
Validity and reliability of behavioural status measures used in treatment eff...
Validity and reliability of behavioural status measures used in treatment efficacy studies in Alzheimer’s Dementia (n = 13). -
Distribution for the sensitivity (SEN) (%) and specificity (SPE) (%) for the ...
Distribution for the sensitivity (SEN) (%) and specificity (SPE) (%) for the healthy control (HC), Alzheimer’s disease (AD) and Parkinson’s disease (PD) groups, accuracy (ACC)... -
r37980778c78--72863fa0d97e1fa06d473e90665dbc5b
A, Each circle is indicating the numbers of either up or down regulated genes by oxidative stress, aging in the cerebrum and in the cerebellum. Five genes were up-regulated and... -
r37980778c78--2588fe3e827e641c0faea5779962ae45
Locations of the proximal entry tears and torn outlets of the intimal flap shown on the conventional CT. -
Meta-analyses of comparative efficacy of antidepressant medications on periph...
BackgroundBrain derived neurotrophic factor (BDNF) is one of the most important regulatory proteins in the pathophysiology of major depressive disorder (MDD). Increasing numbers... -
r37980778c78--232573ec99f3cc0662c169bb9ce66c0f
Characteristics of study population between sedative-hypnotics exposure and non-exposure. -
r37980778c78--b90bd3d4ed4117bfcf50fc6700b4bc34
People with Down syndrome (DS) are at high risk of developing Alzheimer disease (AD) with aging. The diagnosis and treatment trials are hampered by a lack of reliable blood... -
Induction of Pla2g3 expression in cerebrum by oxidative stress.
A, B, Quantitative RT-PCR results of Pla2g3 in cerebrum and cerebellum are shown. Fold changes to the aged wild-type mice on normal diet are indicated. n = 4 in each group. C,...