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Relative efficacy of different types of exercise for treatment of knee and hi...
Background ‘Exercise’ is universally recommended as a core treatment for knee and hip osteoarthritis (OA). However, there are very few head-to-head comparative trials to... -
Integrated mental health care and vocational rehabilitation to improve return...
Background Depression and anxiety are among the largest contributors to the global burden of disease and have negative effects on both the individual and society. Depression and... -
ALternatives To prophylactic Antibiotics for the treatment of Recurrent urina...
Background At least half of all adult women will experience infective cystitis (urinary tract infection: UTI) at least once in their life and many suffer from repeated episodes.... -
Dealing with daily challenges in dementia (deal-id study): effectiveness of t...
Background There is an urgent need for psychosocial interventions that effectively support dementia caregivers in daily life. The Experience Sampling Methodology (ESM) offers... -
Optimising pain management in children with acute otitis media through a prim...
Whilst current guidelines highlight the importance of pain management for children with acute otitis media (AOM), there is evidence to suggest that this is not implemented in... -
Background, design and conceptual model of the cluster randomized multiple-co...
Background Several RCT studies have aimed to reduce either musculoskeletal disorders, sickness presenteeism, sickness absenteeism or a combination of these among females with... -
Application of causal inference methods in the analyses of randomised control...
Background Applications of causal inference methods to randomised controlled trial (RCT) data have usually focused on adjusting for compliance with the randomised intervention... -
"Outcomes of a four-year specialist-taught physical education program on phys...
Background The objective of this study was to investigate the effect of a 4-year specialist-taught Physical Education (PE) program on physical activity (PA) among primary school... -
Operative hysteroscopy versus vacuum aspiration for incomplete spontaneous ab...
Background Incomplete spontaneous abortions are defined by the intrauterine retention of the products of conception after their incomplete or partial expulsion. This condition... -
Cognitive Bias Modification for paranoia (CBM-pa):study protocol for a random...
Background Persecutory delusions are the most common type of delusions in psychosis and present in around 10–15% of the general population. Persecutory delusions are thought to... -
MOVING: Motivation-Oriented interVention study for the elderly IN Greifswald:...
Background Cardiovascular diseases (CVD) are the leading cause of mortality. In 2014, they were responsible for 38.9% of all causes of death in Germany. One major risk factor... -
Does additional support provided through e-mail or SMS in a Web-based Social ...
Background The FAN Social Marketing program was developed to improve dietary and physical activity habits of families with children in Ticino, Switzerland. The aim of this study... -
Integrated mental health care and vocational rehabilitation to improve return...
Background Common mental disorders are important contributors to the global burden of disease and cause negative effects on both the individual and society. Stress-related... -
Robot Assisted Training for the Upper Limb after Stroke (RATULS): study proto...
Background Loss of arm function is a common and distressing consequence of stroke. We describe the protocol for a pragmatic, multicentre randomised controlled trial to determine... -
B-positive: A randomized controlled trial of a multicomponent positive psycho...
Background Bipolar disorder (BD) is characterized by recurrent (hypo)manic and depressive episodes, alternating with euthymic states in which patients are relatively symptom... -
Hedonic Adaptation to Treatment: Evidence from a Medical Intervention
We investigate whether changes in life circumstances lead to long-lasting changes in subjective well-being using a medical intervention that provided orthotic equipment to... -
A single-blind, dose escalation, phase I study of high-fluence light-emitting...
Background Skin fibrosis is involved in a variety of pathologic conditions ranging from scar formation secondary to surgery or trauma to immune-mediated processes. Skin fibrosis... -
Individualised short-term therapy for adolescents impaired by attention-defic...
Background Despite the high persistence rate of attention-deficit/hyperactivity disorder (ADHD) throughout the lifespan, there is a considerable gap in knowledge regarding... -
The Fear Reduction Exercised Early (FREE) approach to low back pain: study pr...
Background Low back pain (LBP) is a major health issue associated with considerable health loss and societal costs. General practitioners (GPs) play an important role in the... -
Effectiveness of enhanced cognitive behavioral therapy (CBT-E) for eating dis...
Background While eating disorder not otherwise specified (EDNOS) is the most common eating disorder (ED) diagnosis in routine clinical practice, no specific treatment methods...
