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The outcome of structural heart defects diagnosed in the first trimester of p...
Purpose: We present the results of a detailed protocol of fetal heart examination in the first trimester, in a fetal medicine unit in Romania. Methods: Since October 2009, in... -
Development of an infant feeding core outcome set for childhood obesity inter...
Abstract Background Childhood obesity is a significant public health challenge that affects approximately one in five children worldwide. Infant feeding practices are implicated... -
Cord blood DNA methylation reflects cord blood C-reactive protein levels but ...
Abstract Background Prenatal inflammation has been proposed as an important mediating factor in several adverse pregnancy outcomes. C-reactive protein (CRP) is an inflammatory... -
Specificity versus redundancy in the RAP2.4 transcription factor family of Ar...
Abstract Background The Arabidopsis ERFIb / RAP2.4 transcription factor family consists of eight members with highly conserved DNA binding domains. Selected members have been... -
PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma
Abstract Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead... -
Role of goblet cell protein CLCA1 in murine DSS colitis
Abstract Background The secreted goblet cell protein CLCA1 (chloride channel regulator, calcium-activated-1) is, in addition to its established role in epithelial chloride... -
Fetal sex and maternal pregnancy outcomes: a systematic review and meta-analysis
Abstract Background Since the placenta also has a sex, fetal sex–specific differences in the occurrence of placenta-mediated complications could exist. Objective To determine... -
Subjective and objective assessment of physical activity in multiple sclerosi...
Abstract Background Physical activity (PA) is frequently restricted in people with multiple sclerosis (PwMS) and aiming to enhance PA is considered beneficial in this... -
Point-of-care testing for emergency assessment of coagulation in patients tre...
Abstract Background Point-of-care testing (POCT) of coagulation has been proven to be of great value in accelerating emergency treatment. Specific POCT for direct oral... -
Aberrant intestinal microbiota due to IL-1 receptor antagonist deficiency pro...
Abstract Background Perturbation of commensal intestinal microbiota has been associated with several autoimmune diseases. Mice deficient in interleukin-1 receptor antagonist... -
Effects of an exclusive breastfeeding intervention for six months on growth p...
BACKGROUND: Breastfeeding promotion is regarded as one of the most effective interventions to improve child health, and could reduce under-5-mortality by 8 % globally. Few... -
Determining ‘curriculum viability’ through standards and inhibitors of curric...
Abstract Background A curriculum is dynamic entity and hence, metaphorically, can be considered ‘alive’. Curricular diseases may impair its quality and hence its viability. The... -
Association of endothelial and glycocalyx injury biomarkers with fluid admini...
Abstract Background Injury to endothelium and glycocalyx predisposes to vascular leak, which may subsequently lead to increased... -
Stillbirth in women with diabetes: a retrospective analysis of fetal autopsy ...
Introduction: Diabetes in pregnancy is associated with an increased rate of stillbirth. There are a wide variety of factors that have been implicated including placental... -
Characterizing ice particles using two-dimensional reflections of a lidar beam
This is an Open Access article published by The Optical Society under the terms of the Creative Commons Attribution 4.0 License. Further distribution of this work must maintain... -
Prognostic DNA methylation markers for sporadic colorectal cancer: a systemat...
Abstract Background Biomarkers that can predict the prognosis of colorectal cancer (CRC) patients and that can stratify high-risk early stage patients from low-risk early stage... -
Urine NGAL as a biomarker for septic AKI: a critical appraisal of clinical ut...
Abstract Background Neutrophil gelatinase-associated lipocalin (NGAL) is released from kidney tubular cells under stress as well... -
Applying GRADE-CERQual to qualitative evidence synthesis findings—paper 2: ho...
Abstract Background The GRADE-CERQual (Confidence in Evidence from Reviews of Qualitative research) approach has been developed by the GRADE (Grading of Recommendations... -
Prognostic DNA methylation markers for hormone receptor breast cancer: a syst...
Abstract Background In patients with hormone receptor-positive breast cancer, differentiating between patients with a low and a high risk of recurrence is an ongoing challenge.... -
Improving reporting of meta-ethnography: the eMERGe reporting guidance
Abstract Aims The aim of this study was to provide guidance to improve the completeness and clarity of meta-ethnography reporting. Background Evidence-based policy and practice...