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Structural peculiarities and anticancer activities of two organotin compounds
Two new organotin compounds, triphenyl-4,6-diamine-pyrimidine-2-thione-tin(IV) (1) and triphenyl-imidazoline-2-thione-chloro-tin(IV) (2), have been synthesized,... -
dedup_wf_001--843f878f841a1288a96c177ca30db65a
Background. A phase Ia/b dose-escalation study was performed to characterize the safety, efficacy and pharmacokinetic properties of the oral small molecule insulin-like growth... -
DRD3 (dopamine receptor D3) but not DRD2 activates autophagy through MTORC1 i...
Growing evidence shows that autophagy is deficient in neurodegenerative and psychiatric diseases, and that its induction may have beneficial effects in these conditions....