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r37980778c78--a53b45f678a186371e2191f6aa1b0375
Due to its function in the rate limiting initial step of the renin-angiotensin system, renin is a particularly promising target for drugs designed to control hypertension, a... -
Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...
Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a... -
r37980778c78--a28ed8ff797935171b0b49b640680875
A novel highly ordered three-dimensional mesoporous carbon-nitride-based hybrid material (MCN-2) with very high surface area, pore volume, and a possible cage type porous... -
r37980778c78--4fa6fd7840f1d95caef27d374c09d7c0
The Tibetan Plateau is described as the “Roof of the World” averaging over 4000 m above sea level; it is remote, isolated, and presumed to be a pristine region. In order to... -
r37980778c78--20d5cb9ef2131f7c2f5fd1f5ab7c3f3a
The development of n-pentenyl furanosyl donors has been tested using arabinose as a model. The readily prepared ortho ester (NPOE) is converted into disarmed (NPGAC) and thence... -
r37980778c78--252888beeb39cd495d9bb7020a9e08fd
This study presents the determination and comparison of isotopic compositions of Hg in sediments, plankton, roach, and perch of two freshwater systems in the Lake Baikal−Angara... -
dedup_wf_001--08efdaeacfabe46954c22f54971b41d6
In this poster different mathematical models describing the heat transfer mechanisms through porous materials were analyzed. They were compared respectively fitted to measured... -
Academic Meta Tool – Ein RDF basiertes Web-Tool zur Modellierung des Zweifels...
Zur interoperablen und semantischen Modellierung von Forschungsdaten in den Geistes- und Kulturwissenschaften werden z.B. Graphstrukturen wie Linked Data verwendet. Gängige... -
Sagittamides A and B. Polyacetoxy Long-Chain Acyl Amino Acids from a Didemnid...
An unidentified tunicate from Pohnpei, Micronesia, yielded sagittamides A and Bcompounds comprising a long-chain C26 dicarboxylic acid that acylates terminal l-valine and... -
Design and Synthesis of Potent Cystine-Free Cyclic Hexapeptide Agonists at th...
Cyclic hexapeptides, incorporating a dipeptide unit in place of the disulfide bond found in urotensin, were prepared and screened at the human urotensin receptor. The bridging... -
Emission Energy Correlates with Inverse of Gold−Gold Distance for Various [Au...
A series of bis(thiocyanato)gold(I) complexes with Au−Au interactions show luminescence in the range from 500 to 670 nm. The series of salts correlates emission energy with the... -
r37980778c78--45c77806280e278526960e808d2b7b2b
Electrolysis of benzylthiocyanate, benzyl chloride, p-methylbenzyl chloride, p-methoxybenzyl chloride, or toluene in acetonitrile, at platinum electrodes in a two compartments... -
Organically Templated Linear and Layered Iron Sulfates
Linear and layered organically templated iron sulfates have been prepared under hydrothermal conditions. The linear iron sulfates, with the compositions... -
Extension of a Charged Anisotropic United Atoms Model to Polycyclic Aromatic ...
A new potential model for polycyclic aromatic hydrocarbons has been developed on the basis of a charged anisotropic united atoms (AUA) potential with six AUA force centers and... -
r37980778c78--dc688d4e05796af49e5270c3398ec0a1
EuAgxAl11−x phases adopting the BaHg11-type structure (space group Pm3̅m, Z = 3) were synthesized with high yield by arc melting a mixture loaded as “EuAg3.5Al7.5” and annealing... -
CAUTION: Popular "Benchmark" Data Sets Do Not Distinguish the Merits of 3D QS...
The quality of 3D QSAR models obtained using extremely simple descriptors was examined for nine popular data sets, including the well-known set of 31 steroids, which for 20... -
r37980778c78--0d58b247fc6ccdfa396b3b16263c79da
A novel kind of magnetic core/mesoporous silica shell nanospheres with a uniform particle diameter of ca. 270 nm was synthesized. The inner magnetic core endues the whole... -
Solid-Phase Synthesis of Bicyclic Dipeptide Mimetics by Intramolecular Cycliz...
A general strategy for the solid-phase synthesis of structurally diverse bicyclic dipeptide mimetics is presented. Depending on the amino acid side-chain (R1), peptide-derived... -
MOESM2 of A phase I study of high-dose rosuvastatin with standard dose erloti...
Additional file 2: Figure S2. Serum marker levels in Patient 11 who developed rhadbomyolysis on study. Baseline and Day 6 (erlotinib only) serum levels in the normal range for... -
r37980778c78--8cb26c1184e90ec8981a194d23b14ab8
The reaction kinetics of chlorine atoms with a series of partially fluorinated straight-chain alcohols, CF3CH2CH2OH (1), CF3CF2CH2OH (2), CHF2CF2CH2OH (3), and CF3CHFCF2CH2OH...
