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Prioritising pathogens for the management of severe febrile patients to impro...
Abstract Background Severe febrile illness without a known source (SFWS) is a challenge for clinicians when deciding how to manage a patient, particularly given the wide... -
Immune responses upon Campylobacter jejuni infection of secondary abiotic mic...
Abstract Background Campylobacter jejuni infections are of rising importance worldwide. Given that innate immune receptors including nucleotide-oligomerization-domain-2 (Nod2)... -
Transient detectable viremia and the risk of viral rebound in patients from t...
Abstract Background Temporary increases in plasma HIV RNA ('blips') are common in HIV patients on combination antiretroviral therapy (cART). Blips above 500 copies/mL have been... -
High prevalence of IgG antibodies to Ebola virus in the Efé pygmy population ...
Abstract Background Factors related to the natural transmission of Ebola virus (EBOV) to humans are still not well defined. Results of previous sero-prevalence studies suggest... -
Acute ileitis facilitates infection with multidrug resistant Pseudomonas aeru...
Abstract Background The rising incidence of multidrug resistant (MDR) Gram-negative bacteria including Pseudomonas aeruginosa has become a serious issue in prevention of its... -
Occurrence of marked sepsis-induced immunosuppression in pediatric septic sho...
Abstract Background While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric... -
The cost of influenza-associated hospitalizations and outpatient visits in Kenya
Background: We estimated the cost-per-episode and the annual economic burden associated with influenza in Kenya. Methods: From July 2013–August 2014, we recruited patients with... -
Campylobacter jejuni infection of conventionally colonized mice lacking nucle...
Abstract Background The nucleotide-binding oligomerisaton protein 2 (NOD2) constitutes a pivotal sensor of bacterial muramyl dipeptide and assures expression of distinct... -
Potential impact of multiple interventions on HIV incidence in a hyperendemic...
Abstract Background Multiple prevention interventions, including early antiretroviral therapy initiation, may reduce HIV incidence in hyperendemic settings. Our aim was to... -
dedup_wf_001--2e0bc162b122a3d566233f9782f6ecde
Increased vaccine hesitancy presents challenges to public health and undermines efforts to eradicate diseases such as measles, rubella, and polio. The decline is partly... -
Efficacy of imidacloprid 10%/moxidectin 1% spot-on formulation (Advocate®) in...
Abstract Background In three randomized, controlled laboratory efficacy studies, the efficacy in the prevention of patent infections of a topical combination of imidacloprid... -
Characterisation of clinical, laboratory and imaging factors related to mild ...
Background: Early detection of disease progression associated with severe COVID-19, and access to proper medical care lowers fatality rates of severe cases. Currently, no... -
Measles seroprevalence after reactive vaccination campaigns during the 2015 m...
Abstract Background Measles continues to circulate in the Democratic Republic of Congo, and the country suffered from several important outbreaks over the last 5 years. Despite... -
Simple descriptive missing data indicators in longitudinal studies with attri...
Abstract Objective Missing data in longitudinal studies may constitute a source of bias. We suggest three simple missing data indicators for the initial phase of getting an... -
Changes in pneumococcal carriage prevalence and factors associated with carri...
Abstract Background Streptococcus pneumoniae carriage is often asymptomatic but can cause invasive pneumococcal disease. Pneumococcal carriage is a prerequisite for disease,... -
Carvacrol ameliorates acute campylobacteriosis in a clinical murine infection...
Abstract Background The prevalence of human infections with the zoonotic pathogen Campylobacter jejuni is rising worldwide. Therefore, the identification of compounds with...
