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Prioritising pathogens for the management of severe febrile patients to impro...
Abstract Background Severe febrile illness without a known source (SFWS) is a challenge for clinicians when deciding how to manage a patient, particularly given the wide... -
Self-monitoring of health data by patients with a chronic disease: does disea...
Background: There is a growing emphasis on self-monitoring applications that allow patients to measure their own physical health parameters. A prerequisite for achieving... -
dedup_wf_001--39c2dd95fe4025379e9d8a43a1fbbcaf
Manipulation of the microbiome is an emerging approach to promote health. We conducted a Phase Ia safety study of a single bladder instillation of probiotics in asymptomatic... -
Risk perception of blood transfusions – a comparison of patients and allied h...
Background: Due to an increasing demand in health care services plans to substitute selective physician-conducted medical activities have become attractive. Because... -
Effect of procalcitonin-guided antibiotic treatment on clinical outcomes in i...
Background: The clinical utility of serum procalcitonin levels in guiding antibiotic treatment decisions in patients with sepsis remains unclear. This patient-level... -
A transcriptomic snapshot of early molecular communication between Pasteuria ...
© The Author(s). 2018 -
Occurrence of marked sepsis-induced immunosuppression in pediatric septic sho...
Abstract Background While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric... -
dedup_wf_001--2e0bc162b122a3d566233f9782f6ecde
Increased vaccine hesitancy presents challenges to public health and undermines efforts to eradicate diseases such as measles, rubella, and polio. The decline is partly... -
Efficacy of imidacloprid 10%/moxidectin 1% spot-on formulation (Advocate®) in...
Abstract Background In three randomized, controlled laboratory efficacy studies, the efficacy in the prevention of patent infections of a topical combination of imidacloprid... -
Measles seroprevalence after reactive vaccination campaigns during the 2015 m...
Abstract Background Measles continues to circulate in the Democratic Republic of Congo, and the country suffered from several important outbreaks over the last 5 years. Despite... -
Simple descriptive missing data indicators in longitudinal studies with attri...
Abstract Objective Missing data in longitudinal studies may constitute a source of bias. We suggest three simple missing data indicators for the initial phase of getting an... -
Changes in pneumococcal carriage prevalence and factors associated with carri...
Abstract Background Streptococcus pneumoniae carriage is often asymptomatic but can cause invasive pneumococcal disease. Pneumococcal carriage is a prerequisite for disease,... -
Seroprevalence and risk factors of recent infection with hepatitis E virus du...
Abstract Background From September 2016–April 2017, Am Timan, Chad, experienced a large HEV outbreak in an urban setting with a limited impact in terms of morbidity and... -
Frequency and impact of confounding by indication and healthy vaccinee bias i...
Background: Evidence on influenza vaccine effectiveness (VE) is commonly derived from observational studies. However, these studies are prone to confounding by indication and...
