53 items found

Types: other Groups: figshare Tags: Genetics Medicine mesheuropmc.eye diseases

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    Eye Biometry Using Quantitatve 3-D OCT

    Cataracts cause the crystalline lens of the eye to progressively lose its transparency, which decreases vision. It is one of the major causes of vision loss in our aging...
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    Novel mutation in the CHST6 gene causes macular corneal dystrophy in a black ...

    Abstract Background Macular corneal dystrophy (MCD) is a rare autosomal recessive disorder that is characterized by progressive corneal opacity that starts in early childhood...
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    Twenty-five years of optical coherence tomography: the paradigm shift in sens...

    Optical coherence tomography (OCT) has become one of the most successful optical technologies implemented in medicine and clinical practice mostly due to the possibility of...
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    Multimodal adaptive optics retinal imager: design and performance

    Optical coherence tomography (OCT) and scanning laser ophthalmoscopy (SLO) are complementary imaging modalities, the combination of which can provide clinicians with a wealth of...
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    Extracellular vesicles derived from human ES-MSCs protect retinal ganglion ce...

    Abstract Background Retinal and/or optic nerve injury is one of the leading causes of blindness due to retinal ganglion cell (RGC) degeneration. There have been extensive...
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    Vision-related quality of life considering both eyes: results from the German...

    Abstract Purpose Most definitions of visual impairment focus on the status of the better-seeing eye only, but this approach might underestimate the influence of the worse-seeing...
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    The neuroregenerative effects of topical decorin on the injured mouse cornea

    Abstract Background The cornea is innervated with a rich supply of sensory nerves that play important roles in ocular surface health. Any injury or pathology of the corneal...
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    Retinal glial responses to optic nerve crush are attenuated in Bax-deficient ...

    Abstract Background Retinal ganglion cell (RGC) soma death is a consequence of optic nerve damage, including in optic neuropathies like glaucoma. The activation of the innate...
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    The association between socioeconomic status and visual impairments among pri...

    Abstract Background Glaucoma is one of the most leading causes of permanent visual impairments in Korea, and social expenses spent for the glaucoma are increasing. This study is...
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    Temporal multiplexing with adaptive optics for simultaneous vision

    We present and test a methodology for generating simultaneous vision with a deformable mirror that changed shape at 50 Hz between two vergences: 0 D (far vision) and −2.5 D...
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    Progressive optic nerve changes in cavitary optic disc anomaly: integration o...

    Abstract Background We performed clinical and genetic characterization of a family with cavitary optic disc anomaly (CODA), an autosomal dominant condition that causes vision...
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    Not only dominant, not only optic atrophy: expanding the clinical spectrum as...

    Abstract Background Heterozygous mutations in OPA1 are a common cause of autosomal dominant optic atrophy, sometimes associated with extra-ocular manifestations. Few cases...
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    A novel nonsense mutation in the tyrosinase gene is related to the albinism i...

    Abstract Background Oculocutaneous Albinism (OCA) is an autosomal recessive inherited condition that affects the pigmentation of eyes, hair and skin. The OCA phenotype may be...
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    Polarization-sensitive swept-source optical coherence tomography with continu...

    We present fiber-based polarization-sensitive swept-source optical coherence tomography (SS-OCT) based on continuous source polarization modulation. The light source is a...
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    Development and validation of a novel PCR-RFLP based method for the detection...

    Abstract Background Leber’s Hereditary Optic Neuropathy (LHON; MIM 535000) is one of the most commonly inherited optic neuropathies and it results in significant visual...
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    Dynamic OCT measurement of corneal deformation by an air puff in normal and c...

    A new technique is presented for the non-invasive imaging of the dynamic response of the cornea to an air puff inducing a deformation. A spectral OCT instrument combined with an...
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    Segmentation error in spectral domain optical coherence tomography measures o...

    Abstract Background Optical Coherence Tomography (OCT) imaging is being increasingly used in clinical practice for the monitoring of papilloedema. The aim is to characterise the...
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    Choroidal vascular changes in retinitis pigmentosa patients detected by optic...

    Abstract Background To evaluate choroidal vascular changes, including choriocapillaris (CC) and middle/large choroidal vessels, in retinitis pigmentosa (RP) patients using...
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    Symmetry of Disease in Retinopathy of Prematurity in the Postnatal Growth and...

    To determine the symmetry of retinopathy of prematurity (ROP) between fellow eyes in a broad-risk cohort. A retrospective cohort study, the Postnatal Growth and ROP (G-ROP)...
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    Is it necessary to use tobramycin-dexamethasone eye ointment prophylactically...

    Abstract Background There are no data available regarding the complications associated with using antibiotic ointment at the end of intraocular surgery. This study aimed to...