595 items found

Types: other Groups: figshare Tags: Computational Biology Developmental Biology

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    Continue, adjust, or stop antipsychotic medication: developing and user testi...

    Abstract Background People with psychosis struggle with decisions about their use of antipsychotics. They often want to reduce the dose or stop, while facing uncertainty...
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    MRI of trunk muscles and motor and respiratory function in patients with myot...

    Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to...
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    Early gut microbiota signature of aGvHD in children given allogeneic hematopo...

    Abstract Background The onset of acute Graft-versus-Host Disease (aGvHD) has been correlated with the gut microbiota (GM) composition, but experimental observations are still...
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    Genetic tool for fate mapping of Oct4 (Pou5f1)-expressing cells and their pro...

    Abstract Background Methods based on site-specific recombinases are widely used in studying gene activities in vivo and in vitro. In these studies, constitutively active or...
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    Boron-deficiency-responsive microRNAs and their targets in Citrus sinensis le...

    Abstract Background MicroRNAs play important roles in the adaptive responses of plants to nutrient deficiencies. Most research, however, has focused on nitrogen (N), phosphorus...
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    Factors associated with the development of septic shock in patients with cand...

    Abstract Background Almost one third of the patients with candidemia develop septic shock. The understanding why some patients do and others do not develop septic shock is very...
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    Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb del...

    Abstract Background Oculocutaneous albinism (OCA) is an autosomal recessive disorder. A significant portion of OCA patients has been found with a single pathogenic variant...
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    Survey indicated that core outcome set development is increasingly including ...

    Abstract Background There are numerous challenges in including patients in a core outcome set (COS) study, these can vary depending on the patient group. This study describes...
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    Probiotics may not prevent the deterioration of necrotizing enterocolitis fro...

    Abstract Background Probiotic therapy can reduce the incidence of NEC. Therapeutic use of probiotics after NEC diagnosis reduces the severity of NEC in preterm infants or...
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    Sex hormones affect endothelial lipase-mediated lipid metabolism and atherosc...

    Abstract Background Endothelial lipase (EL) plays an important role in lipoprotein metabolism and atherosclerosis. To study the functional roles of EL, we recently generated...
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    Identification of interchangeable cross-species function of elongation factor...

    Abstract Background Tick-borne Babesia bigemina is responsible for acute and potentially lethal hemolytic disease in cattle. The development of genetic manipulation tools...
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    Appendectomy, cholecystectomy and diagnostic laparoscopy conducted before pre...

    Abstract Background Non-obstetric surgery conducted during pregnancy may increase the risk of adverse birth outcomes like small for gestational age, preterm birth, and...
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    Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen...

    Abstract Background Nuclear receptor family member, Estrogen related receptor β, and the Hedgehog signal transduction pathway are both reported to relate to tumorigenesis and...
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    Molecular characterization of flavanone 3-hydroxylase gene and flavonoid accu...

    Abstract Background Among secondary metabolites, flavonoids are particularly crucial for plant growth, development, and reproduction, as well as beneficial for maintenance of...
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    Efficient frequency comb generation in AlGaAs-on-insulator

    The combination of nonlinear and integrated photonics enables Kerr frequency comb generation in stable chip-based micro-resonators. Such a comb system will revolutionize...
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    Vasoresponsiveness in patients with heart failure (VASOR): protocol for a pro...

    Abstract Background Vasoplegia is a severe complication which may occur after cardiac surgery, particularly in patients with heart failure. It is a result of activation of...
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    The architecture of national boundary regimes: mapping immigration and citize...

    Abstract In this article, I introduce a typology that maps the regulation of two fundamental boundaries of modern nation-states regarding immigration: territorial boundaries and...
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    Diaper dermatitis: a survey of risk factors in Thai children aged under 24 mo...

    Abstract Background To identify the prevalence and risk factors associated with diaper dermatitis in Thai children aged 1–24 months. Methods This was a cross-sectional study of...
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    Rice transcription factor OsMADS57 regulates plant height by modulating gibbe...

    Abstract Background The MADS-box transcription factors mainly function in floral organ organogenesis and identity specification. Few research on their roles in vegetative growth...
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    Fluid removal associates with better outcomes in critically ill patients rece...

    Abstract Background Fluid overload is associated with morbidity and mortality in patients receiving renal replacement therapy (RRT). We aimed to explore whether fluid overload...