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Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen...
Abstract Background Nuclear receptor family member, Estrogen related receptor β, and the Hedgehog signal transduction pathway are both reported to relate to tumorigenesis and... -
Quality assessment of clinical practice guidelines for chronic kidney disease...
Abstract Background Chronic kidney disease (CKD) is a worldwide public health problem. Clinical practice guidelines (CPGs) are being developed and implemented in order to... -
LncRNA LUADT1 sponges miR-15a-3p to upregulate Twist1 in small cell lung cancer
Abstract Lung adenocarcinoma associated transcript 1 (LUADT1) has been reported as an oncogenic long non-coding RNA (lncRNA) in lung adenocarcinoma, while its roles in small... -
Intraflagellar transport proteins are involved in thrombocyte filopodia forma...
Intraflagellar transport (IFT) proteins are vital for the genesis and maintenance of cilia. Our identification of ift122 transcripts in zebrafish thrombocytes that lack primary... -
The pioneer factor activity of c-Myb involves recruitment of p300 and inducti...
Abstract Background The concept of pioneer transcription factors is emerging as an essential part of the epigenetic regulation, taking place during cell development and... -
BMP-SMAD signalling output is highly regionalized in cardiovascular and lymph...
Abstract Background Bone morphogenetic protein (BMP) signalling has emerged as a fundamental pathway in endothelial cell biology and deregulation of this pathway is implicated... -
Drosophila Netrin-B controls mushroom body axon extension and regulates court...
Abstract Mushroom body (MB) is a prominent structure essential for olfactory learning and memory in the Drosophila brain. The development of the MB involves the appropriate... -
STAT3 enhances the constitutive activity of AGC kinases in melanoma by transa...
Abstract Background The PI3K/Akt and the STAT3 pathways are functionally associated in many tumor types. Both in vitro and in vivo studies have revealed that either biochemical...
