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MRI of trunk muscles and motor and respiratory function in patients with myot...
Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to... -
Rubidium and potassium levels are altered in Alzheimer’s disease brain and bl...
Abstract Loss of intracellular compartmentalization of potassium is a biochemical feature of Alzheimer’s disease indicating a loss of membrane integrity and mitochondrial... -
Dried blood spot versus venous blood sampling for phenylalanine and tyrosine
Abstract Background This study investigated the agreement between various dried blood spot (DBS) and venous blood sample measurements of phenylalanine and tyrosine... -
Involvement of ABC-transporters and acyltransferase 1 in intracellular choles...
Abstract Background Understanding pathogenic mechanisms is imperative for developing novel treatment to the tuberculosis, an important public health burden worldwide. Recent... -
Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Effects of Text-to-Speech Software Use on the Reading Proficiency of High Sch...
Effects of Text-to-Speech Software Use on the Reading Proficiency of High School Struggling Readers -
Lung function reductions associated with motor vehicle density in chronic obs...
Abstract Background Motor vehicle-related air pollution can potentially impair lung function. The effect of pollution in people with compromised pulmonary function such as in... -
Differences in lipid metabolism between anagliptin and sitagliptin in patient...
Abstract Background Anagliptin, a dipeptidyl peptidase-4 inhibitor, is reported to reduce the level of low-density lipoprotein cholesterol (LDL-C). The underlying mechanism of... -
The whole - genome expression analysis of peripheral blood mononuclear cells ...
Abstract Background Up to 30 % of adults with severe asthma are hypersensitive to aspirin and no unambiguous theory exists which provides a satisfactory explanation for the... -
Effects of oxytocin administration on salivary sex hormone levels in autistic...
Abstract Background Oxytocin administration, which may be of therapeutic value for individuals with social difficulties, is likely to affect endogenous levels of other socially... -
Differential expression of E-type prostanoid receptors 2 and 4 in microglia s...
Abstract Background Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E2 (PGE2) is one of the products of COX activity. PGE2 has pleiotropic... -
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits...
Abstract Background Systemic inflammation is associated with increased cognitive decline and risk for Alzheimer’s disease. Microglia (MG) activated during systemic inflammation... -
Phosphodiesterases in non-neoplastic appearing colonic mucosa from patients w...
Abstract Background Intracellular signaling through cyclic nucleotides, both cyclic AMP and cyclic GMP, is altered in colorectal cancer. Accordingly, it is hypothesized that an... -
Identification of plasma microRNA expression changes in multiple system atrop...
Abstract MicroRNAs (miRNAs) are endogenous small (18–25 nt), single-stranded, non-coding RNAs that play key roles in post-transcriptional gene expression regulation. The... -
High cholesterol induces apoptosis and autophagy through the ROS-activated AK...
Abstract Background Hypercholesterolemia increases the risk of tendon pain and tendon rupture. Tendon-derived stem cells (TDSCs) play a vital role in the development of... -
The impact of biological sex on the response to noise and otoprotective thera...
Abstract Background Noise-induced hearing loss (NIHL) is the most prevalent form of acquired hearing loss and affects about 40 million US adults. Among the suggested... -
iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated d...
Abstract Background Previous research indicated that nitric oxide synthase (NOS) is the key molecule for S-nitrosylation of ryanodine receptor 1 (RyR1) in DMD model mice (mdx... -
Transcriptomic data from two primary cell models stimulating human monocytes ...
Abstract Background Biological interpretation of DNA microarray data may differ depending on underlying assumptions and statistical tests of bioinformatics tools used. We used... -
Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in p...
Abstract Background Transient receptor potential ankyrin 1 (TRPA1) is a membrane-associated cation channel, widely expressed in neuronal cells and involved in nociception and... -
Progesterone ameliorates diabetic nephropathy in streptozotocin-induced diabe...
Abstract Background Previous studies reported that 17β-estradiol may influence the progression of diabetic renal disease in females. The present study was intended to provide an...
