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Omalizumab in patients with severe asthma and persistent sputum eosinophilia
Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who... -
Effects of Text-to-Speech Software Use on the Reading Proficiency of High Sch...
Effects of Text-to-Speech Software Use on the Reading Proficiency of High School Struggling Readers -
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling p...
Abstract Background Runt-related transcription factor 1 (RUNX1) plays the roles of an oncogene and an anti-oncogene in epithelial tumours, and abnormally elevated RUNX1 has been... -
Novel three-dimensional bone ‘mapping’ software can help assess progression o...
Abstract Imaging of bone metastasis response to therapy is a research priority. Stradwin is a new software-tool, with demonstrated sub-voxel accuracy in assessing cortical bone... -
ABO antigen and secretor statuses are not associated with gut microbiota comp...
Abstract Background Host genetics is one of several factors known to shape human gut microbiome composition, however, the physiological processes underlying the heritability are... -
CDC42 controls the activation of primordial follicles by regulating PI3K sign...
Abstract Background In mammalian females, progressive activation of dormant primordial follicles in adulthood is crucial for the maintenance of the reproductive lifespan.... -
Guiding electron orbits with chirped light
We demonstrate that chirped light is effective in shrinking or expanding a class of nonspreading electron eigenstate wave packets in Rydberg atoms. -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
Using virtual worlds as a platform for collaborative meetings in healthcare: ...
Abstract Background Healthcare teams often consist of geographically dispersed members. Virtual worlds can support immersive, high-quality, multimedia interaction between remote... -
Additional file 10: of lncRNA profile of Apis mellifera and its possible role...
The top 20 enriched KEGG pathways of differentially expressed mRNAs from the three comparison groups. (XLS 31 kb) -
The index of prediction accuracy: an intuitive measure useful for evaluating ...
Abstract Background Many measures of prediction accuracy have been developed. However, the most popular ones in typical medical outcome prediction settings require additional... -
Ready, Set, Change! Development and usability testing of an online readiness ...
Abstract Background To address challenges related to selecting a valid, reliable, and appropriate readiness assessment measure in practice, we developed an online decision... -
Noninvasive label-free imaging of microhemodynamics by optical-resolution pho...
In vivo microcirculatory imaging facilitates the fundamental understanding of many major diseases. However, existing techniques generally require invasive procedures or... -
Nigella A ameliorates inflammation and intestinal flora imbalance in DSS indu...
Abstract Nigella A, also named Sieboldianoside A, has been extracted from many kinds of Traditional Chinese Medicine (TCM), such as Nigella glandulifera, Stauntonia chinensis... -
Untangling performance from success
Abstract Fame, popularity and celebrity status, frequently used tokens of success, are often loosely related to, or even divorced from professional performance. This dichotomy... -
The Ussing chamber system for measuring intestinal permeability in health and...
Abstract Background The relationship between intestinal epithelial integrity and the development of intestinal disease is of increasing interest. A reduction in mucosal... -
Computed tomography derived bone density measurement in the diabetic foot
Abstract Background The accurate and reliable measurement of foot bone density is challenging and there is currently no gold standard technique. Such measurement is particularly... -
Accurate determination of node and arc multiplicities in de bruijn graphs usi...
Abstract Background De Bruijn graphs are key data structures for the analysis of next-generation sequencing data. They efficiently represent the overlap between reads and hence,... -
A-Lister: a tool for analysis of differentially expressed omics entities acro...
Abstract Background Researchers commonly analyze lists of differentially expressed entities (DEEs), such as differentially expressed genes (DEGs), differentially expressed... -
The intestinal microbiota regulates host cholesterol homeostasis
Abstract Background Management of blood cholesterol is a major focus of efforts to prevent cardiovascular diseases. The objective of this study was to investigate how the gut...
