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The magnitude of antibiotic resistance to Helicobacter pylori in Africa and i...
Abstract Background Worldwide Helicobacter pylori (H.pylori) treatment is of great challenge due to increased antibiotic resistance. The burden of H. pylori antibiotic... -
808 nm-activable core@multishell upconverting nanoparticles with enhanced sta...
Abstract Background The unique upconversion properties of rare-earth-doped nanoparticles offers exciting opportunities for biomedical applications, in which near-IR remote... -
Design, synthesis and biological activity of hydroxybenzoic acid ester conjug...
Abstract We prepared 16 novel hydroxybenzoic acid ester conjugates of phenazine-1-carboxylic acid (PCA) and investigated their biological activity. Most of the synthesized... -
Ambiguity of non-systematic chemical identifiers within and between small-mol...
Abstract Background A wide range of chemical compound databases are currently available for pharmaceutical research. To retrieve compound information, including structures,... -
Suppression of endothelial cell migration by tumor associated macrophage-deri...
Abstract Objective To study the mechanism by which epithelial ovarian cancer (EOC)-derived exosomes restore the migration of endothelial cells that is suppressed by TAM-derived... -
The Ussing chamber system for measuring intestinal permeability in health and...
Abstract Background The relationship between intestinal epithelial integrity and the development of intestinal disease is of increasing interest. A reduction in mucosal... -
Epigenetically upregulated oncoprotein PLCE1 drives esophageal carcinoma angi...
Abstract Background Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies. Neovascularization during tumorigenesis supplies oxygen and nutrients to... -
Gastric Parietal Cell and Intestinal Goblet Cell Secretion: a Novel Cell-Medi...
Abstract Up to date, the way in which metal nanoparticles are cleared in vivo has yet to be elucidated well. Herein, we report a novel intestinal goblet cell-mediated in vivo... -
Autologous bone marrow stem cell transplantation via the hepatic artery for t...
Abstract Objective Autologous bone marrow stem cell (ABMSC) transplantation has been considered a promising option for hepatitis B virus-related cirrhosis (HBV-C). Although an... -
An automated pipeline for analyzing medication event reports in clinical sett...
Abstract Background Medication events in clinical settings are significant threats to patient safety. Analyzing and learning from the medication event reports is an important... -
Tyrosinase inhibitory activity of flavonoids from Artocarpus heterophyllous
Abstract Background Tyrosinase is an oxidoreductase that is very important in medicine and cosmetics because the excessive production of melanin causes hyperpigmentation. The... -
Vascular assessment techniques of podiatrists in Australia and New Zealand: a...
Abstract Background Podiatrists play a central role in conducting non-invasive vascular assessment in the lower extremity. This involves screening for signs and symptoms of... -
Treatments of residual pine strands: characterization and wood-cement-compati...
This paper aims to evaluate treatments on pine strands as well as wood-cement compatibility. The strands were prepared and then were submitted to four treatments (untreated;... -
Aerosol delivery during invasive mechanical ventilation: a systematic review
Abstract Background This systematic review aimed to assess inhaled drug delivery in mechanically ventilated patients or in animal models. Whole lung and regional deposition and... -
A meta-analysis of the effect of a dexamethasone intravitreal implant versus ...
Abstract Background This meta-analysis evaluated the effectiveness and safety of dexamethasone (DEX) implant and intravitreal anti-vascular endothelial growth factor (VEGF)... -
Adverse events during oral colchicine use: a systematic review and meta-analy...
Abstract Background Colchicine is a widely used drug to treat inflammatory diseases. Due to its long historical use in medicine, controlled clinical trials have been small and... -
Radiolabeling polymeric micelles for in vivo evaluation: a novel, fast, and f...
Abstract Background Single photon emission computed tomography (SPECT) is an indispensable tool in the determination of the in vivo fate of polymeric micelles. However, for this... -
Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macroph...
Abstract Introduction Methotrexate (MTX) induces macrophage apoptosis in vitro, but there is not much evidence for increased synovial macrophage apoptosis in MTX-treated... -
Adipose-derived stem cells prevent the onset of bisphosphonate-related osteon...
Abstract Background Due to its complex pathogenesis and low clinical cure rate, bisphosphonate-related osteonecrosis of the jaw (BRONJ) poses a substantial challenge for oral... -
Umbilical cord/placenta-derived mesenchymal stem cells inhibit fibrogenic act...
Abstract Background The lack of anti-fibrotic agents targeting intestinal fibrosis is a large unmet need in inflammatory bowel diseases, including Crohn’s disease and ulcerative...
