-
Using predicate and provenance information from a knowledge graph for drug ef...
Abstract Background Biomedical knowledge graphs have become important tools to computationally analyse the comprehensive body of biomedical knowledge. They represent knowledge... -
Saturated absorption competition microscopy
Owing to the advantage of being non-invasive in observing living samples, far-field optical microscopy is widely used in the life sciences, but the existence of the diffraction... -
Assessing the external validity of algorithms to estimate EQ-5D-3L from the W...
Abstract Background The use of mapping algorithms have been suggested as a solution to predict health utilities when no preference-based measure is included in the study.... -
Comparing structural fingerprints using a literature-based similarity benchmark
Abstract Background The concept of molecular similarity is one of the central ideas in cheminformatics, despite the fact that it is ill-defined and rather difficult to assess... -
Identifying diabetes cases from administrative data: a population-based valid...
Abstract Background Health care data allow for the study and surveillance of chronic diseases such as diabetes. The objective of this study was to identify and validate optimal... -
A virtual clinic for the management of diabetes-type 1: study protocol for a ...
Abstract Background Diabetes is a serious chronic disease. Medical treatment and good psychosocial support are needed to cope with acute and long-term effects of diabetes.... -
Gene name errors are widespread in the scientific literature
Abstract The spreadsheet software Microsoft Excel, when used with default settings, is known to convert gene names to dates and floating-point numbers. A programmatic scan of... -
Development of a benchmark tool for cancer centers; results from a pilot exer...
Abstract Background Differences in cancer survival exist between countries in Europe. Benchmarking of good practices can assist cancer centers to improve their services aiming... -
Acceleration of integral imaging based incoherent Fourier hologram capture us...
Speed enhancement of integral imaging based incoherent Fourier hologram capture using a graphic processing unit is reported. Integral imaging based method enables exact hologram... -
A radiomics-based model on non-contrast CT for predicting cirrhosis: make the...
Abstract Background To establish and validate a radiomics-based model for predicting liver cirrhosis in patients with hepatitis B virus (HBV) by using non-contrast computed... -
Andrographis paniculata transcriptome provides molecular insights into tissue...
Abstract Background Kalmegh (Andrographis paniculata) has been widely exploited in traditional medicine for the treatment of infectious diseases and health disorders.... -
Organoids of epithelial ovarian cancer as an emerging preclinical in vitro to...
Abstract Epithelial ovarian cancer (EOC) remains the most lethal gynecological cancer in developed countries, indicating the need for further research. Although current cancer... -
Algorithms for imputing partially observed recurrent events with applications...
Five algorithms are described for imputing partially observed recurrent events modeled by a negative binomial process, or more generally by a mixed Poisson process when the mean... -
RUNX1 promotes tumour metastasis by activating the Wnt/β-catenin signalling p...
Abstract Background Runt-related transcription factor 1 (RUNX1) plays the roles of an oncogene and an anti-oncogene in epithelial tumours, and abnormally elevated RUNX1 has been... -
Ambiguity of non-systematic chemical identifiers within and between small-mol...
Abstract Background A wide range of chemical compound databases are currently available for pharmaceutical research. To retrieve compound information, including structures,... -
Design and assessment of a wide FOV and high-resolution optical tiled head-mo...
It has always been a challenge to break the resolution/field-of-view (FOV) invariant to design a large FOV and high-resolution optical system, especially for a head-mounted... -
Novel three-dimensional bone ‘mapping’ software can help assess progression o...
Abstract Imaging of bone metastasis response to therapy is a research priority. Stradwin is a new software-tool, with demonstrated sub-voxel accuracy in assessing cortical bone... -
Brownian fluctuations of an optically rotated nanorod
Gold nanorods can be optically trapped in aqueous solution and forced to rotate at kilohertz rates by circularly polarized laser light. This enables detailed investigations of... -
Cloud designs and deployment models: a systematic mapping study
Abstract Background Cloud computing is a unique paradigm that is aggregating resources available from cloud service providers for use by customers on demand and pay per use... -
Clinical action measures improve the reliability of feedback on quality of ca...
Abstract Background Assessment of quality of care using classical threshold measures (TM) is open to debate. Measures that take into account the clinician’s actions and the...
