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Self-directed learning readiness of Indian medical students: a mixed method s...
Abstract Background Self-directed learning (SDL) is defined as learning on oneâ s own initiative, with the learner having primary responsibility for planning, implementing, and... -
Prevalence and characteristics of older adults with a persistent death wish w...
Abstract Background Some older persons develop a persistent death wish without being severely ill, often referred to as “completed life” or “tiredness of life”. In the... -
Erythropoietin as an add-on treatment for cognitive side effects of electroco...
Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments... -
Pathological complete response due to a prolonged time interval between preop...
Abstract Background Preoperative chemoradiotherapy is the recommended standard of care for patients with local advanced rectal cancer. However, it remains unclear, whether a... -
Ca2+ in the dorsal raphe nucleus promotes wakefulness via endogenous sleep-wa...
Abstract Serotonergic neurons in the dorsal raphe nucleus (DRN) are involved in the control of sleep-wake states. Our previous studies have indicated that calcium (Ca2+)... -
Appendectomy, cholecystectomy and diagnostic laparoscopy conducted before pre...
Abstract Background Non-obstetric surgery conducted during pregnancy may increase the risk of adverse birth outcomes like small for gestational age, preterm birth, and... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Effects of gestational diabetes mellitus on risk of adverse maternal outcomes...
Abstract Background Gestational diabetes mellitus is a leading medical condition woman encounter during pregnancy with serious short- and long-term consequences for maternal... -
Open-label versus double-blind placebo treatment in irritable bowel syndrome:...
Abstract Background Placebo medications, by definition, are composed of inactive ingredients that have no physiological effect on symptoms. Nonetheless, administration of... -
Degree of dyspnoea at admission and discharge in patients with heart failure ...
Abstract Background Dyspnoea is a disabling symptom in patients admitted with heart failure (HF) and respiratory diseases (RD). The main aim of this study is to evaluate its... -
Systematic review of outcome domains and instruments used in clinical trials ...
Abstract Background There is no evidence-based guidance to facilitate design decisions for confirmatory trials or systematic reviews investigating treatment efficacy for adults... -
Combination of Ranibizumab with macular laser for macular edema secondary to ...
Abstract Background It is not clear whether macular laser combined with anti-vascular endothelial growth factor (VEGF) can reduce the number of anti-VEGF injections in the... -
Effect of smoking status on lung function, patient-reported outcomes, and saf...
Abstract Background Smoking is a major risk factor for COPD and may impact the efficacy of COPD treatments; however, a large proportion of COPD patients continue to smoke... -
Suppression of LPS-induced tau hyperphosphorylation by serum amyloid A
Abstract Background Accumulation of hyperphosphorylated tau is a major neuropathological feature of tauopathies including Alzheimer’s disease (AD). Serum amyloid A (SAA), an... -
Transient receptor potential ankyrin 1 (TRPA1) is functionally expressed in p...
Abstract Background Transient receptor potential ankyrin 1 (TRPA1) is a membrane-associated cation channel, widely expressed in neuronal cells and involved in nociception and... -
Memory retrieval in addiction: a role for miR-105-mediated regulation of D1 r...
Abstract Background Drug addiction is a chronic brain disorder characterized by the compulsive use of drugs. The study of chronic morphine-induced adaptation in the brain and... -
Postpartum women’s use of medicines and breastfeeding practices: a systematic...
Abstract The objectives of this article are to systematically review i) the extent of medicine use in postpartum women, and ii) the impact of maternal medicine use (excluding... -
Comparability of three intraocular pressure measurement: iCare pro rebound, n...
Abstract Background Measurement of intraocular pressure (IOP) is essential for glaucoma patients. Many factors such as central corneal thickness (CCT) can affect the accuracy of... -
Do Cochrane summaries help student midwives understand the findings of Cochra...
Abstract Background Abstracts and plain language summaries (PLS) are often the first, and sometimes the only, point of contact between readers and systematic reviews. It is... -
The smoking cessation in pregnancy incentives trial (CPIT): study protocol fo...
Abstract Background Eighty per cent of UK women have at least one baby, making pregnancy an opportunity to help women stop smoking before their health is irreparably...
