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Status of metered dose inhaler technique among patients with asthma and its e...
Abstract Objective In Asthma management, poor handling of inhalation devices and wrong inhalation technique are associated with decreased medication delivery and poor disease... -
Association between sexual violence and unintended pregnancy among adolescent...
Abstract Background Unintended pregnancy has dire consequences on the health and socioeconomic wellbeing of adolescent girls and young women (AGYW) (aged 15–24 years). While... -
Pediatric asthma comprises different phenotypic clusters with unique nasal mi...
Abstract Background Pediatric asthma is the most common chronic childhood disease in the USA, currently affecting ~ 7 million children. This heterogeneous syndrome is thought to... -
Detailed analysis of sputum and systemic inflammation in asthma phenotypes: a...
Abstract Background The technique of induced sputum has allowed to subdivide asthma patients into inflammatory phenotypes according to their level of granulocyte airway... -
Development and validation of a score to identify in the Emergency Department...
Abstract Background Risk stratification methods developed on the basis of predicting illness severity are often used to prioritise patients on the basis of urgency. Illness... -
Lifetime secondhand smoke exposure and childhood and adolescent asthma: findi...
Abstract Background Secondhand smoke (SHS) exposure is a modifiable risk factor associated with childhood asthma. Associations with adolescent asthma and the relevance of the... -
Polygenic risk for coronary heart disease acts through atherosclerosis in typ...
Abstract Background Type 2 diabetes increases the risk of coronary heart disease (CHD), yet the mechanisms involved remain poorly described. Polygenic risk scores (PRS) provide... -
MaveDB: an open-source platform to distribute and interpret data from multipl...
Abstract Multiplex assays of variant effect (MAVEs), such as deep mutational scans and massively parallel reporter assays, test thousands of sequence variants in a single... -
Application of machine learning methodology to assess the performance of DIAB...
Abstract Background The study aimed to assess the performance of a multidisciplinary-team diabetes care program called DIABETIMSS on glycemic control of type 2 diabetes (T2D)... -
Predictive factors for sepsis by carbapenem resistant Gram-negative bacilli i...
Abstract Background Studies have investigated risk factors for infections by specific species of carbapenem-resistant Gram-negative bacilli (CR-GNB), but few considered the... -
Comparison of hypothesis- and data-driven asthma phenotypes in NHANES 2007–20...
Abstract Background Half of the adults with current asthma among the US National Health and Nutrition Examination Survey (NHANES) participants could be classified in more than... -
Impaired type I interferon regulation in the blood transcriptome of recurrent...
Abstract Background Asthma exacerbations are an important cause of morbidity in asthma. Respiratory infections are often involved in asthma exacerbations in both children and... -
An artificially simulated outbreak of a respiratory infectious disease
Abstract Background Outbreaks of respiratory infectious diseases often occur in crowded places. To understand the pattern of spread of an outbreak of a respiratory infectious... -
Simulating ComBat: how batch correction can lead to the systematic introducti...
Abstract Background Systematic technical effects—also called batch effects—are a considerable challenge when analyzing DNA methylation (DNAm) microarray data, because they can... -
Additional file 2: of lncRNA profile of Apis mellifera and its possible role ...
The distribution of reads mapped to reference annotation. (XLS 25 kb) -
Antimicrobial peptide similarity and classification through rough set theory ...
Abstract Background Antimicrobial peptides attract considerable interest as novel agents to combat infections. Their long-time potency across bacteria, viruses and fungi as part... -
Copy number variants in the sheep genome detected using multiple approaches
Abstract Background Copy number variants (CNVs) are a type of polymorphism found to underlie phenotypic variation, both in humans and livestock. Most surveys of CNV in livestock... -
Construction of possible integrated predictive index based on EGFR and ANXA3 ...
Abstract Background Variability in drug response between individual patients is a serious concern in medicine. To identify single-nucleotide polymorphisms (SNPs) related to drug... -
Co-circulation of coxsackieviruses A-6, A-10, and A-16 causes hand, foot, and...
Abstract Background Hand, foot, and mouth disease (HFMD) is a common infectious disease occurring in children under 5 years of age worldwide, and Enterovirus A71 (EV-A71) and... -
Development and validation of a diagnostic model for early differentiation of...
Abstract Background Since early antimicrobial therapy is mandatory in septic patients, immediate diagnosis and distinction from non-infectious SIRS is essential but hampered by...
