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Climate factors driven typhus group rickettsiosis incidence dynamics in Xishu...
Abstract Background Typhus group rickettsiosis (TGR), which is a neglected vector-borne infectious disease, including epidemic typhus and endemic typhus. We explored the lag... -
Detection of lipoarabinomannan (LAM) in urine is an independent predictor of ...
Abstract Background Simple immune capture assays that detect mycobacterial lipoarabinomannan (LAM) antigen in urine are promising new tools for the diagnosis of HIV-associated... -
Combined interventions to reduce HIV incidence in KwaZulu-Natal: a modelling ...
Abstract Background Combined prevention interventions, including early antiretroviral therapy initiation, may substantially reduce HIV incidence in hyperendemic settings. Our... -
Relation of multi-marker panel to incident chronic kidney disease and rapid k...
Abstract Background Few investigations have evaluated the incremental usefulness of multiple biomarkers representing varying physiological pathways for predicting risk of renal... -
Use of biologically-based complementary medicine in breast and gynecological ...
Abstract Background Biologically-based complementary medicines (BB-CAM) including herbs and nutritional supplements are frequently taken by breast- and gynecological cancer... -
Outcomes of community-based differentiated models of multi-month dispensing o...
Abstract Background Current World Health Organization (WHO) guidelines recommend early initiation of HIV positive patients on antiretroviral therapy (ART) irrespective of their... -
Mathematical models for devising the optimal Ebola virus disease eradication
Abstract Background The 2014â 2015 epidemic of Ebola virus disease (EVD) in West Africa defines an unprecedented health threat for human. Methods We construct a mathematical... -
Factors associated with loss-to-follow-up of HIV-positive mothers and their i...
Abstract Background In Malawi, loss to follow-up (LTFU) of HIV-positive pregnant and postpartum women on Option B+ regimen greatly contributes to sub-optimal retention,... -
A randomized, 29-day, dose-ranging, efficacy and safety study of daprodustat,...
Abstract Background Daprodustat is a hypoxia-inducible factor-prolyl hydroxylase inhibitor currently being investigated as a treatment for anemia of chronic kidney disease (CKD)... -
Anemia prevalence and incidence and red blood cell transfusion practices in a...
Abstract Background Whether a restrictive strategy for red blood cell (RBC) transfusion is applied to patients with aneurysmal subarachnoid hemorrhage (aSAH) is unclear. To... -
Using record linkage to validate notification and laboratory data for a more ...
Abstract Background Infectious disease burden is commonly assessed using notification data. Using retrospective record linkage in Western Australia, we described how well... -
Polygenic risk for coronary heart disease acts through atherosclerosis in typ...
Abstract Background Type 2 diabetes increases the risk of coronary heart disease (CHD), yet the mechanisms involved remain poorly described. Polygenic risk scores (PRS) provide... -
The evaluation of enhanced feedback interventions to reduce unnecessary blood...
Abstract Background Blood for transfusion is a frequently used clinical intervention, and is also a costly and limited resource with risks. Many transfusions are given to stable... -
Pooling for SARS-CoV-2 control in care institutions
Abstract Background Workers and residents in Care Homes are considered at special risk for the acquisition of SARS-CoV-2 infection, due to the infectivity and high mortality... -
Quality of family planning services in HIV integrated and non-integrated heal...
Abstract Background The integration of family planning (FP) and HIV-related services is common in sub-Saharan Africa. Little research has examined how FP quality of care differs... -
Estimating transmission probability in schools for the 2009 H1N1 influenza pa...
Abstract Background Epidemic models are being extensively used to understand the main pathways of spread of infectious diseases, and thus to assess control methods. Schools are... -
Tuberculosis and its association with CD4+ T cell count among adult HIV posit...
Abstract Background Tuberculosis (TB) and HV have been intertwined and makeup a deadly human syndemic worldwide, especially in developing countries like Ethiopia. Previous... -
Pleuropneumonectomy for a large thymoma with multiple pleural dissemination u...
Abstract We present 2 cases of a large thymoma with invasion to the hilum of the lung and pleural dissemination. Case 1: a 47-year-old woman was diagnosed with a type B3 thymoma... -
Diabetes incidence and projections from prevalence surveys in Fiji
Abstract Background Type 2 diabetes mellitus (T2DM) incidence is traditionally derived from cohort studies that are not always feasible, representative, or available. The... -
Oseltamivir in pregnancy and birth outcomes
Abstract Background Prenatal exposure to influenza or fever is associated with risk of congenital malformations. Oseltamivir is used to treat influenza and to provide...
