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BAX-BAK1-independent LC3B lipidation by BH3 mimetics is unrelated to BH3 mime...
Inhibition of prosurvival BCL2 family members can induce autophagy, but the mechanism is controversial. We have provided genetic evidence that BCL2 family members block... -
Stakeholder perspectives on the implementation of genetic carrier screening i...
Abstract Background In most countries, genetic carrier screening is neither offered, nor embedded in mainstream healthcare. Technological developments have triggered a two-fold... -
Reported bed net ownership and use in social contacts is associated with upta...
Abstract Background Despite progress made in the last decades, malaria persists as a pressing health issue in sub-Saharan Africa. Pregnant women are particularly vulnerable to... -
Microbial survey of ready-to-eat salad ingredients sold at retail reveals the...
Abstract Background As the preparation of salads involves extensive handling and the use of uncooked ingredients, they are particularly vulnerable to microbial contamination.... -
Single nucleotide polymorphisms in apoptosis pathway are associated with resp...
Abstract Background The mechanism of action of imatinib is known to involve the Fas-mediated apoptosis pathway. Consequently inter-individual variations in this apoptosis... -
Economic cost analysis of malaria case management at the household level duri...
Abstract Background In China, malaria has been posing a significant economic burden on households. To evaluate malaria economic burden in terms of both direct and indirect costs... -
Additional file 2: of The HIV Care Cascade from HIV diagnosis to viral suppre...
Complete cascade including all steps. A) HIV care cascade as defined by the WHO, B) Assessment of ART eligibility within the HIV care cascade. ART, antiretroviral therapy; D,... -
Financial barriers and coping strategies: a qualitative study of accessing mu...
Abstract Background Tuberculosis (TB) and multidrug-resistance tuberculosis (MDR-TB) pose serious challenges to global health, particularly in China, which has the second... -
MOESM2 of The epidemiology of residual Plasmodium falciparum malaria transmis...
Additional file 2. ExcelÂŽ spreadsheet summaries of sampled households and participants. -
Influenza-like illness in an urban community of Salvador, Brazil: incidence, ...
Abstract Background Our understanding of the epidemiology of influenza is limited in tropical regions, which in turn has hampered identifying optimal region-specific policy to... -
Deprotonation and Addition Reactions of Frustrated Lewis Pairs with Alkynes
Deprotonation of terminal alkynes is effected by the treatment with tBu3P and B(C6F5)3 to give [tBu3PH][PhCCB(C6F5)3] (1a) and [tBu3PH][RCCB(C6F5)3] (R = nBu 2, tBu 3, Me3Si 4,... -
MOESM6 of Posterior eyespots in larval chitons have a molecular identity simi...
Additional file 6: Figure S4. Shielding pigment test. (A) After treating the specimen with acidified Methanol the eye pigment spot completely fades. (B) After transferring the... -
Quantitative evaluation of the strategy to eliminate human African trypanosom...
Abstract Background The virulent vector-borne disease, Gambian human African trypanosomiasis (HAT), is one of several diseases targeted for elimination by the World Health... -
Pharmacological regimens for eradication of Helicobacter pylori: an overview ...
Abstract Background Approximately half of the worldâ s population is infected with Helicobacter pylori (H.pylori), a bacterium shown to be linked with a series of... -
Additional file 2: of Host-pathogen interplay at primary infection sites in p...
Hierarchical cluster analysis of FTIR spectroscopic data recorded from A. pleuropneumoniae serotype 2 after 2 and 5 passages under laboratory conditions. After re-isolation from... -
Sidearm Effects. Synthesis, Structural Characterization, and Reactivity of Ra...
New ether-functionalized carboranyl-indenyl hybrid ligands were prepared. They can prevent lanthanocene chlorides from ligand redistribution reactions and offer samarium(II)... -
Household costs of dengue illness: secondary outcomes from a randomised contr...
Abstract Background Dengue is a serious public health problem with an important economic impact. This study used data from a cluster randomised controlled trial of community... -
Additional file 2: Table S2. of Identification and annotation of conserved pr...
Table S2A â Locations of FANTOM5 human promoters mapped to the pig genome. Table contains the following columns (left to right): FANTOM5 human promoter ID, Ensembl gene ID... -
Geostatistical space–time mapping of house prices using Bayesian maximum entropy
Mapping spatial processes at a small scale is a challenge when observed data are not abundant. The article examines the residential housing market in Fort Worth, Texas, and... -
Predictors of delayed culture conversion among Ugandan patients
Abstract Background Estimates of month-2 culture conversion, a proxy indicator of tuberculosis (TB) treatment efficacy in phase-2 trials can vary by culture-type and...
