-
Intravenous iron isomaltoside versus oral iron supplementation for treatment ...
Abstract Background Iron deficiency is common in pregnancy. If left untreated, iron deficiency can lead to iron deficiency anaemia, which is a condition related to maternal and... -
Characteristics of sleep/wake problems and delivery outcomes among pregnant J...
Abstract Background Frequently observed sleep/wake problems among pregnant women need comprehensive evaluation. This study was conducted to clarify the sleep/wake problems among... -
Motor cortex and pain control: exploring the descending relay analgesic pathw...
Abstract Motor cortex stimulation (MCS) is an effective therapy for refractory neuropathic pain. MCS increases the nociceptive threshold in healthy rats via endogenous opioids,... -
Effectiveness of the addition of therapeutic alliance with minimal interventi...
Abstract Background The stratified model of care has been an effective approach for the treatment of low back pain. However, the treatment of patients with low risk of... -
Predictors of instantaneous relief from spinal manipulation for non-specific ...
Abstract Background There is some evidence and anecdotal reports that high-velocity low-amplitude (HVLA) spinal manipulation therapy (SMT) for non-specific low back pain (NSLBP)... -
A Phase 2 clinical trial of PF-05212377 (SAM-760) in subjects with mild to mo...
Abstract Background Symptomatic benefits have been reported for 5-HT6 receptor antagonists in Alzheimer’s disease (AD) trials. SAM-760 is a potent and selective 5-HT6 receptor... -
The impact of D-cycloserine and sarcosine on in vivo frontal neural activity ...
Abstract Background N-methyl-D-aspartate receptor (NMDAR) hypofunction has been proposed to underlie the pathogenesis of schizophrenia. Specifically, reduced function of NMDARs... -
Associations of subjective and objective clinical outcomes of visual function...
Abstract Background The cost of managing a chronic disease like glaucoma is quite large. A convenient and economical monitoring tool like self-reported measures of Quality of... -
Tonic and burst spinal cord stimulation waveforms for the treatment of chroni...
Abstract Background Burst stimulation is a novel form of neurostimulation for the treatment of chronic pain which has demonstrated promise in small uncontrolled studies, but has... -
Hospital utilization rates following antipsychotic dose reduction in mood dis...
Abstract Background The relative benefits and risks of long-term maintenance treatment with antipsychotics have not been well studied in patients with bipolar disorder and major... -
Full versus half dose of antenatal betamethasone to prevent severe neonatal r...
Abstract Background Although antenatal betamethasone is recommended worldwide for women at risk of preterm delivery, concerns persist regarding the long-term effects associated... -
Endo-lysosomal dysregulations and late-onset Alzheimer’s disease: impact of g...
Abstract Increasing evidence supports that cellular dysregulations in the degradative routes contribute to the initiation and progression of neurodegenerative diseases,... -
Lifestyle intervention to prevent excessive maternal weight gain: mother and ...
Abstract Background Excessive gestational weight gain (GWG) is associated with elevated weight retention in mothers and might be related to adiposity of their offspring. Little... -
Using smartphones to decrease substance use via self-monitoring and recovery ...
Abstract Background Alcohol abuse, other substance use disorders, and risk behaviors associated with the human immunodeficiency virus (HIV) represent three of the top 10... -
Genetic deletion or pharmacological inhibition of soluble epoxide hydrolase r...
Abstract Background Inflammatory responses significantly contribute to neuronal damage and poor functional outcomes following intracerebral hemorrhage (ICH). Soluble epoxide... -
Silica nanoparticles induce neurodegeneration-like changes in behavior, neuro...
Abstract Background Silica nanoparticles (SiO2-NPs) are naturally enriched and broadly utilized in the manufacturing industry. While previous studies have demonstrated toxicity... -
Cocaine-mediated induction of microglial activation involves the ER stress-TL...
Abstract Background Neuroinflammation associated with advanced human immunodeficiency virus (HIV)-1 infection is often exacerbated by chronic cocaine abuse. Cocaine exposure has... -
Neuropsychological profiles of adult bipolar disorder patients with and witho...
Abstract Background Comorbid attention-deficit/hyperactivity disorder (ADHD) is common in bipolar disorder and associated with worse outcomes. Cognitive testing might be a tool... -
Microglial depletion and repopulation in brain slice culture normalizes sensi...
Abstract Background Microglia are critical mediators of neuroimmune pathology across multiple neurologic disorders. Microglia can be persistently activated or “primed” by...
