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Profile of the 2016 dengue outbreak in Nepal
Abstract Objective The objective of this study was to obtain clinical, virological and demographic data detailing the 2016 dengue outbreak in Nepal. Results Dengue disease was... -
Lst1 deficiency has a minor impact on course and outcome of the host response...
Abstract Background Previously, we performed a quantitative trait locus (QTL) mapping study in BXD recombinant inbred mice to identify host genetic factors that confer... -
Murine host response to Neisseria gonorrhoeae upper genital tract infection r...
Abstract Background The emergence of fully antimicrobial resistant Neisseria gonorrhoeae has led global public health agencies to identify a critical need for next generation... -
Variability in intensive care unit admission among pregnant and postpartum wo...
Abstract Background Pregnancy-related critical illness results in approximately 300,000 deaths globally each year. The objective was to describe the variation in ICU admission... -
Removal of totally implanted venous access ports for suspected infection in t...
Abstract Background While no data support this practice, international guidelines recommend the removal of totally implanted venous access ports (TIVAPs) in patients with... -
Electrolyte outpatient clinic at a local hospital – experience from diagnosti...
Abstract Background Electrolyte imbalances (EI) are common among patients. Many patients have repeated hospitalizations with the same EI without being investigated and treated.... -
Which bronchodilator reversibility criteria can predict severe acute exacerba...
Abstract Background It is unclear whether various bronchodilator reversibility (BDR) criteria affect the prognosis of chronic obstructive pulmonary disease (COPD). The aim of... -
Health-related quality of life in persons with West Nile virus infection: a l...
Abstract Background West Nile virus (WNV) infections are predominantly asymptomatic, although almost 1% become neuroinvasive and debilitating. We describe the impact of... -
TLR8 regulation of LILRA3 in monocytes is abrogated in human immunodeficiency...
Abstract Background LILRA3 is an immunostimulatory molecule which can conditionally induce the proliferation of cytotoxic cells. LILRA3 has a deletion genotype which is... -
The development of a global chiropractic rehabilitation competency framework ...
Abstract The World Health Organization (WHO), in its “Rehabilitation 2030 A Call for Action”, identified the need to strengthen rehabilitation in health systems to meet the... -
Pelvic floor rehabilitation to improve functional outcome and quality of life...
Abstract Background After low anterior resection (LAR), up to 90% of patients develop anorectal dysfunction. Especially fecal incontinence has a major impact on the physical,... -
Prevalence and risk factors for patient-reported joint pain among patients wi...
Abstract Background To determine the prevalence of patient-reported joint pain among patients with human immunodeficiency virus (HIV)/chronic hepatitis C virus (HCV)... -
Characteristics of functional enrichment and gene expression level of human p...
Abstract Background Transcriptional target genes show functional enrichment of genes. However, how many and how significantly transcriptional target genes include functional... -
Undergraduate medical research in the Gulf Cooperation Council (GCC) countrie...
Abstract Objective There is a lack of research-oriented physicians in several Arab countries and especially in Gulf region countries. In this context, it is important to explore... -
Cerebellar ataxia and sensory ganglionopathy associated with light-chain myeloma
Abstract Background Cerebellar ataxia with sensory ganglionopathy is a rare neurological combination that can occur in some hereditary ataxias including mitochondrial diseases... -
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeuti...
Abstract Background The Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the... -
Microbial community shifts elicit inflammation in the caecal mucosa via the G...
Abstract Background Dietary structure in ruminants is closely connected with the composition of gastrointestinal microbiota. Merging study has shown that dietary induced SARA... -
"Not just a normal mum": a qualitative investigation of a support service for...
Abstract Background Following previous perinatal loss, women in a subsequent pregnancy may experience heightened emotions, such as anxiety and fear, with a range of longer-term... -
Experiences of ICU survivors in a low middle income country- a multicenter study
Abstract Background Stressful patient experiences during the intensive care unit (ICU) stay is associated with reduced satisfaction in High Income Countries (HICs) but has not... -
Effects of different principles of Traditional Chinese Medicine treatment on ...
Abstract Background Influenza virus is a single-stranded RNA virus that causes influenza in humans and animals. About 600 million people around the world suffer from influenza...