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Risk factors for hospitalized patients with resistant or multidrug-resistant ...
Abstract Background Identifying risk factors predicting acquisition of resistant Pseudomonas aeruginosa will aid surveillance and diagnostic initiatives and can be crucial in... -
Genetic evaluation of the effect of GLCCI1 rs37973 on corticosteroid response...
Abstract Background The efficacy of inhaled corticosteroids (ICS) for chronic obstructive pulmonary disease (COPD) varies between patients, which may be partially due to genetic... -
Molecular epidemiology and virulence characteristics of Staphylococcus aureus...
Abstract Background Medical laboratory staff are a high-risk population for colonization of Staphylococcus aureus (S. aureus) due to direct and dense contact with the pathogens;... -
Predictors of delayed culture conversion among Ugandan patients
Abstract Background Estimates of month-2 culture conversion, a proxy indicator of tuberculosis (TB) treatment efficacy in phase-2 trials can vary by culture-type and... -
Clinical features and outcomes of seven patients with COVID-19 in a family cl...
Abstract Background The family cluster is one of most important modes of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission throughout China, and more... -
Prevalence and risk factors for patient-reported joint pain among patients wi...
Abstract Background To determine the prevalence of patient-reported joint pain among patients with human immunodeficiency virus (HIV)/chronic hepatitis C virus (HCV)... -
Clinical course & management of childhood nephrotic syndrome in Germany: ...
Abstract Background Nephrotic syndrome (NS) is one of the most frequent occurring chronic kidney diseases in childhood, despite its rarely occurrence in the general population.... -
Epidemiology and burden of influenza in healthy children aged 6 to 35 months:...
Abstract Background Despite World Health Organization recommendations, in many countries young children are not targeted for influenza vaccination. To help inform influenza... -
Analysis of SARS-CoV-2 RNA-dependent RNA polymerase as a potential therapeuti...
Abstract Background The Severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) outbreak originating in Wuhan, China, has raised global health concerns and the... -
Effect of antibiotic pre-treatment and pathogen challenge on the intestinal m...
Abstract Background More than 50Â years after the discovery of antibiotics, bacterial infections have decreased substantially; however, antibiotics also may have negative... -
Carbapenem non-susceptibility of Klebsiella pneumoniae isolates in hospitals ...
Abstract Background Carbapenem resistance in Klebsiella pneumoniae is of significant public health concern and recently spread across several countries. We investigated the... -
Treatment outcomes and antiretroviral uptake in multidrug-resistant tuberculo...
Abstract Background Multidrug-resistant tuberculosis (MDR-TB) in HIV endemic settings is a major threat to public health. MDR-TB is a substantial and underreported problem in... -
30-day readmission, antibiotics costs and costs of delay to adequate treatmen...
Abstract Background Enterobacteriaceae are common pathogens in pneumonia, sepsis and urinary tract infection (UTI). Though rare, carbapenem resistance (CRE) among these... -
Skin microbiota analysis-inspired development of novel anti-infectives
Abstract Background The alarming spread of antimicrobial resistance requires the development of novel anti-infective drugs. Despite the recent research focus on the human... -
Detection of Helicobacter pylori and its virulence genes (cagA, dupA, and vac...
Abstract Background The global prevalence of H. pylori approaches 50%, with prevalence rates between 20 and 40% in developed countries and up to 90% in Africa and other... -
Prognostic value of NT-proBNP in patients with severe COVID-19
Abstract Background The outbreak of coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in China has been declared a... -
Effects of different principles of Traditional Chinese Medicine treatment on ...
Abstract Background Influenza virus is a single-stranded RNA virus that causes influenza in humans and animals. About 600 million people around the world suffer from influenza... -
Inherent bacterial DNA contamination of extraction and sequencing reagents ma...
Abstract Background The advent and use of highly sensitive molecular biology techniques to explore the microbiota and microbiome in environmental and tissue samples have... -
Prevalence of Cryptosporidium, microsporidia and Isospora infection in HIV-in...
Abstract Background Diarrhea caused by opportunistic intestinal protozoa is a common problem in HIV infection. We aimed to establish the prevalence of Cryptosporidium,... -
Prevalence and pattern of antibiotic resistance of Staphylococcus aureus isol...
Abstract Background Studies have implicated Staphylococcus aureus as the leading cause of septicemia in the Tamale metropolis of Ghana. The aim of this study was to determine...
