4,022 items found

Types: other Groups: figshare Tags: Pharmacology

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    Acupuncture as an intervention to reduce alcohol dependency: a systematic rev...

    Abstract Background Acupuncture has been widely used as a treatment for alcohol dependence. An updated and rigorously conducted systematic review is needed to establish the...
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    Correction to: Improved plan quality with automated radiotherapy planning for...

    Abstract In the original publication [1] figure legends 2 and 4 have been swapped. The original article was updated to rectify this error.
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    Erythropoietin as an add-on treatment for cognitive side effects of electroco...

    Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments...
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    Outcomes in pediatric studies of medium-chain acyl-coA dehydrogenase (MCAD) d...

    Abstract Background Inherited metabolic diseases (IMDs) are a group of individually rare single-gene diseases. For many IMDs, there is a paucity of high-quality evidence that...
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    Heterogeneity of cerebral TDP-43 pathology in sporadic amyotrophic lateral sc...

    Abstract Frontotemporal lobar degeneration (FTLD) and amyotrophic lateral sclerosis (ALS) are types of major TDP-43 (43-kDa TAR DNA-binding protein) proteinopathy. Cortical...
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    Use of diagnostic tests and the appropriateness of the treatment decision in ...

    Abstract Background Inappropriate prescription of antibiotics is the leading driver of antimicrobial resistance (AMR). The majority of antibiotics are prescribed in primary...
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    The Video intervention to Inspire Treatment Adherence for Life (VITAL Start):...

    Abstract Background Improving maternal antiretroviral therapy (ART) retention and adherence is a critical challenge facing prevention of mother-to-child transmission (PMTCT) of...
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    Factors that influence the sustainability of structured allied health journal...

    Abstract Background Structured journal clubs are a widely used tool to promote evidence-based practice in health professionals, however some journal clubs (JC) are more...
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    Identifying clinical subgroups in IgG4-related disease patients using cluster...

    Abstract Background To explore the clinical patterns of patients with IgG4-related disease (IgG4-RD) based on laboratory tests and the number of organs involved. Methods...
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    Factors influencing pharmaceutical pricing - a scoping review of academic lit...

    Abstract Introduction Pharmaceutical pricing has only recently gained space in mainstream health science literature. Objectives Bibliometric and content description of health...
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    Risk factors for tuberculosis smear non-conversion in Eden district, Western ...

    Abstract Background Tuberculosis (TB) continues to be a major global health problem. While progress has been made to improve TB cure rates, South Africa’s 76 % smear-positive...
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    Omalizumab in patients with severe asthma and persistent sputum eosinophilia

    Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who...
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    Patient’s perception of kidney stone prevention within the emergency departme...

    Abstract Background No known data in the literature assessing practice of kidney stone prevention in the emergency department (ED) is available. Objectives Assess patient...
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    What happened and why? A programme theory-based qualitative evaluation of a h...

    Abstract Background There is increasing interest in and demands for partnerships between academia and healthcare practices. Few empirical studies have described the influence of...
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    User survey finds rapid evidence reviews increased uptake of evidence by Vete...

    Abstract Background To provide evidence synthesis for faster-paced healthcare decision-making, rapid reviews have emerged as a streamlined alternative to standard systematic...
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    Association between antibiotic consumption and the rate of carbapenem-resista...

    Abstract Background This study aimed to investigate the relationship between the rate of carbapenem-resistant Gram-negative bacteria and antibiotic consumption intensity in 153...
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    The diagnostic accuracy of the hand-held Raman spectrometer for the identific...

    Abstract Background There is a need for accurate and field-applicable instruments for the evaluation of the quality of anti-malarial drugs. The aim of this study was to...
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    Predicting potential adverse events using safety data from marketed drugs

    Abstract Background While clinical trials are considered the gold standard for detecting adverse events, often these trials are not sufficiently powered to detect difficult to...
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    Serum amyloid A primes microglia for ATP-dependent interleukin-1β release

    Abstract Background Acute-phase response is a systemic reaction to environmental/inflammatory insults and involves production of acute-phase proteins, including serum amyloid A...
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    Regulation of STEP61 and tyrosine-phosphorylation of NMDA and AMPA receptors ...

    Abstract Background Sustained changes in network activity cause homeostatic synaptic plasticity in part by altering the postsynaptic accumulation of N-methyl-D-aspartate...