-
Statistical analysis plan for the ‘Tranexamic acid for hyperacute primary Int...
Abstract Rationale Aside from blood pressure lowering, treatment options for intracerebral haemorrhage remain limited and a proportion of patients will undergo early haematoma... -
Netrin-1 attenuates brain injury after middle cerebral artery occlusion via d...
Abstract Background Netrin-1 functions largely via combined receptors and downstream effectors. Evidence has shown that astrocytes express netrin-1 receptors, including DCC and... -
Postural effects on intraocular pressure and ocular perfusion pressure in pat...
Abstract Background To investigate postural effects on intraocular pressure (IOP) and ocular perfusion pressure (OPP) in patients with non-arteritic ischemic optic neuropathy... -
Use of delayed antibiotic prescription in primary care: a cross-sectional study
Abstract Background One of several strategies developed to reduce inappropriate antibiotic use in situations where the indication is not clear is delayed antibiotic prescription... -
Use and perceived added value of patient-reported measurement instruments by ...
Abstract Background This study aims to explore (i) physiotherapists’ current use in daily practice of patient-reported measurement instruments (screening tools and... -
Efficacy differences of electroacupuncture with single acupoint or matching a...
Abstract Background Previous studies have shown that acupuncture is beneficial for the alleviation of chemotherapy-induced nausea and vomiting. However, there is a lack of... -
Improvement of sleep in patients with chronic idiopathic/spontaneous urticari...
Abstract Background Patients with chronic idiopathic/spontaneous urticaria (CIU/CSU) report difficulty with sleep. Methods We examined the effect of omalizumab on sleep-related... -
Thiamine as an adjunctive therapy in cardiac surgery: a randomized, double-bl...
Abstract Background Thiamine is a vitamin that is essential for adequate aerobic metabolism. The objective of this study was to determine if thiamine administration prior to... -
Hippocampal microglial activation triggers a neurotoxic-specific astrocyte re...
Abstract Background Accumulating evidence has highlighted the importance of microglial and astrocyte responses in the pathological development of postoperative cognitive... -
Evaluating the impact of cannabis use on thalamic connectivity in youth at cl...
Abstract Background Disruptions in thalamic functional connectivity have been observed in people with schizophrenia and in youth at clinical high risk (CHR) of psychosis.... -
Donepezil suppresses intracellular Ca2+ mobilization through the PI3K pathway...
Abstract Background Microglia are resident innate immune cells which release many factors including proinflammatory cytokines or nitric oxide (NO) when they are activated in... -
Central mechanisms of real and sham electroacupuncture in the treatment of ch...
Abstract Background Chronic low back pain (CLBP) is the most common chronic pain condition and is often resistant to conventional treatments. Acupuncture is a popular... -
Adequacy of risk of bias assessment in surgical vs non-surgical trials in Coc...
Abstract Background Bias in randomized controlled trials (RCTs) can lead to underestimation or overestimation of the true effects of interventions. Surgical RCTs may suffer from... -
Predictors of instanteous relief from spinal manipulation for non-specific lo...
Abstract Background There is some evidence and anecdotal reports that high-velocity low-amplitude (HVLA) spinal manipulation therapy (SMT) for non-specific low back pain (NSLBP)... -
Resveratrol ameliorates prenatal progestin exposure-induced autism-like behav...
Abstract Background Recent literatures indicate that maternal hormone exposure is a risk factor for autism spectrum disorder (ASD). We hypothesize that prenatal progestin... -
Assessment of chiropractic care on strength, balance, and endurance in active...
Abstract Background Low back pain (LBP) is a common cause of disability among U.S. military personnel. Approximately 20% of all diagnoses resulting in disability discharges are... -
A survey of thrombosis experts evaluating practices and opinions regarding ve...
Abstract Background Patients undergoing major abdominal surgery are at high risk for developing venous thromboembolism in the post-operative period. Current evidence-based... -
Offspring outcomes after prenatal interventions for common mental disorders: ...
Abstract Background It is presumed that pharmacological and non-pharmacological treatment of prenatal common mental disorders can mitigate associated adverse effects in... -
Neuroprotective effect of a novel Chinese herbal decoction on cultured neuron...
Abstract Background Historically, traditional Chinese medicine has been widely used to treat stroke. Based on the theory of Chinese medicine and the modern pharmacological... -
Complement activation contributes to perioperative neurocognitive disorders i...
Abstract Background The complement system plays an important role in many neurological disorders. Complement modulation, including C3/C3a receptor signaling, shows promising...
