824 items found

Organisations: RISIS2OpenData Groups: figshare Tags: Pharmacology Science Policy Virology

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  • dataset

    Novel Manganese(II) Sulfonate−Phosphonates with Dinuclear, Tetranuclear, and ...

    Hydrothermal reactions of manganese(II) salts with m-sulfophenylphosphonic acid (m-HO3S−Ph−PO3H2, H3L) and 1,10-phenanthroline (phen) led to six novel manganese(II)...
  • dataset

    Crystallographic data collection and refinement statistics.

    *Values in parentheses are for highest-resolution shell.aRmerge = Σh Σi|Ii(h)−<I(h)>/|Σh Σi Ii(h), where I is the observed intensity and <I> is the average intensity...
  • dataset

    Demographic data

    **P<0.01; SD, standard deviation; Max/Min, maximal/minimal.The number of participants did not differ between genders (Chi-square P>0.05). The dancer and pianist groups...
  • dataset

    A population-based analysis of the risk of drug interaction between clarithro...

    Abstract Background Clarithromycin, known as a potent inhibitor of the cytochrome P450 isoenzyme CYP3A, may increase the plasma concentration of statins metabolized by this...
  • dataset

    A double-blind, randomised, placebo-controlled study of roxithromycin and dox...

    Abstract Background Azithromycin prophylaxis has been shown to reduce COPD exacerbations but there is poor evidence for other antibiotics. We compared exacerbation rates in COPD...
  • dataset

    A randomized, placebo-controlled study of the cardiovascular safety of the on...

    Abstract Background Omarigliptin is a once-weekly (q.w.) oral DPP-4 inhibitor that is approved for the treatment of patients with type 2 diabetes mellitus (T2DM) in Japan. To...
  • dataset

    How externalities impact an evaluation of strategies to prevent antimicrobial...

    Abstract Background The rates of antimicrobial-resistant organisms (ARO) continue to increase for both hospitalized and community patients. Few resources have been allocated to...
  • dataset

    Media 3: Harmonic extended supercontinuum generation and carrier envelope pha...

    Originally published in Optics Express on 21 July 2008 (oe-16-15-10886)
  • dataset

    r37980778c78--f1e1477b2cfe863e480929adb4bf7847

    [{Ru(η6-p-cymene)(μ-Cl)Cl}2] and [{Ru(η3:η3-C10H16)(μ-Cl)Cl}2] react with Ph2PCH2P{NP(O)(OR)2}Ph2 (R = Et (1a), Ph (1b)) affording complexes...
  • dataset

    Additional file 3: of Medicinal plants – prophylactic and therapeutic optio...

    Assessment of medicinal plants effects in 418 final peer-reviewed references. (XLSX 59 kb)
  • dataset

    Pharmacokinetics and safety of ixazomib plus lenalidomide–dexamethasone in As...

    Abstract Background The oral proteasome inhibitor ixazomib is under phase 3 clinical investigation in multiple myeloma (MM) in combination with lenalidomide–dexamethasone. This...
  • dataset

    IL-6-activated Stat3 binds to the ROR1 promoter and activates transcription i...

    A. ROR1 promoter biotinylated DNA probe binds to nuclear protein of unstimulated or IL-6-stimulated MM1 cells. The addition of an unlabeled (cold) probe attenuated the binding...
  • dataset

    Activation of <i>PPARγ2</i> by PPARγ1 through a functional PPRE in transdiffe...

    PPARγ and Wnt signaling are central positive and negative regulators of adipogenesis, respectively. Here we identified that, eicosapentaenoic acid (EPA) could effectively induce...
  • dataset

    Normal mucus transport is restored in ciliated airway cultures derived from p...

    Normal mucus transport is restored in ciliated airway cultures derived from patients with cystic fibrosis after replacement of the CFTR gene. This image represents yellow...
  • dataset

    Characteristics of patients included in the study.

    CRC, colorectal cancer; NA, not applied. 1Qualitative variables were compared by the Fisher's exact test; continuous variables were compared by the Mann-Whitney U's...
  • dataset

    Reduction in clinically important deterioration in chronic obstructive pulmon...

    Abstract Background ‘Clinically important deterioration’ (CID) is a composite endpoint measuring worsening of the key clinical features of chronic obstructive pulmonary disease...
  • dataset

    MOESM1 of Comparison of anti-malarial drug efficacy in the treatment of uncom...

    Additional file 1. Description of the trials characteristics. The file contains the description within each article in terms of trial characteristics, including the number of...
  • dataset

    Synthesis and Electronic Properties of Isotruxene-Derived Star-Shaped Ladder-...

    The synthesis of star-shaped ladder-type oligophenylenes Sn (n = 4, 7, 10, 13, and 16), where n is the number of π-conjugated phenylene rings, is reported. The two-dimensional...
  • dataset

    Media 1: Simultaneous SLO/OCT imaging of the human retina with axial eye moti...

    Originally published in Optics Express on 10 December 2007 (oe-15-25-16922)
  • dataset

    A Pyrrolyl-Based Triazolophane: A Macrocyclic Receptor With CH and NH Donor G...

    A pyrrolyl-based triazolophane, incorporating CH and NH donor groups, acts as a receptor for the pyrophosphate anion in chloroform solution. It shows selectivity for this...