-
Stereochemical Features of the Physical and Chemical Interactions of Singlet ...
Oxazolidinone-substituted enecarbamates represent a mechanistically rich system for the study of stereoelectronic, steric, and conformational effects on stereoselectivity and... -
Effect of a 17α-(3-Hydroxypropyl)-17β-acetyl Substituent Pattern on the Gluco...
Replacing the 17α-acetoxy substituent in an antiprogestational 17β-acetyl-11β-arylestra-4,9-dien-3-one by 3-hydroxypropyl significantly diminished glucocorticoid receptor... -
Sagittamides A and B. Polyacetoxy Long-Chain Acyl Amino Acids from a Didemnid...
An unidentified tunicate from Pohnpei, Micronesia, yielded sagittamides A and Bcompounds comprising a long-chain C26 dicarboxylic acid that acylates terminal l-valine and... -
Design and Synthesis of Potent Cystine-Free Cyclic Hexapeptide Agonists at th...
Cyclic hexapeptides, incorporating a dipeptide unit in place of the disulfide bond found in urotensin, were prepared and screened at the human urotensin receptor. The bridging... -
Asymmetric Synthesis of Enantioenriched (+)-Elaeokanine A
The key transformation in the total synthesis of (+)-elaeokanine A was accomplished by asymmetric deprotonation of N-Boc pyrrolidine, followed by the reaction of the in situ... -
Identification of a Boron-Containing Intermediate in the Boron Tribromide Med...
An alternate reaction mechanism for the boron tribromide mediated deprotection of aryl propargyl ethers based on the isolation of a key boron-containing byproduct is proposed.... -
Efficient Isomerization of Allyl Ethers and Related Compounds Using Pentacarb...
Efficient Isomerization of Allyl Ethers and Related Compounds Using Pentacarbonyliron -
Electrochemical oxidative iodination of imidazo[1,2-a]pyridines using NaI as ...
An electrochemical oxidative iodination of imidazo[1,2-a]pyridines is achieved in this study. This reaction utilizes NaI as an iodine source and a supporting electrolyte under... -
A Theoretical Study of the Chorismate Synthase Reaction
: Density functional calculations (B3LYP/6-31+G(d,p)) were carried out to investigate the mechanism of the anti-1,4-elimination of phosphate from... -
Synthesis of Optically Active 5-Alkoxy-6-methylcyclohex-2-en-1-ones and 4-Alk...
The reaction of (−)-(1E,3Z)-2-methyl-1-((1S)-1-phenylethoxy)penta-1,3-dien-3-ol benzoate with allyltrimethylsilane in SO2 and in the presence of a catalytic amount of Tf2NTMS... -
Unusual Transannular Cyclization Products of Sarcophytoxide, a 14-Membered Ma...
Treatment of sarcophytoxide with trimethylsilyl trifluoromethanesulfonate afforded an aromatic ketone as an unusual cyclization product. The modified Mosher's method and X-ray... -
Preparation and unequivocal identification of the regioisomers of nitrocatech...
ABSTRACTThe four positional isomers of nitrocatechol monobenzyl ether were prepared as intermediates to nitrobenzodioxanes directly from 2-benzyloxyphenol or, through two-four... -
Impact of Cross-Linking Density and Glassy Chain Dynamics on Pore Stability i...
Mesoporous poly(styrene) (PS) containing various amounts of the cross-linker divinylbenzene was synthesized by a hard-templating routine using pressed pellets of fumed silica as... -
Solid-Phase Synthesis of Bicyclic Dipeptide Mimetics by Intramolecular Cycliz...
A general strategy for the solid-phase synthesis of structurally diverse bicyclic dipeptide mimetics is presented. Depending on the amino acid side-chain (R1), peptide-derived... -
Moisture Effects on <i>Antheraea pernyi</i> Silk’s Mechanical Property
Water plays an essential role in determining the mechanical properties of silks and other structural proteins. Here we study the effects of moisture on the elastic modulus of... -
Reactions of α,α‘-Dihydroxy Ketones with Phosgene. Structural Requirements fo...
α,α‘-Dihydroxy ketones having two OH groups that can come into close proximity react with phosgene in the presence of DMAP to produce 1,3-dioxane-2,5-diones. When covalent... -
dedup_wf_001--a5872e4a60793df7a1620d00ba7b863c
This work reports the first investigation on the physical vapor deposition of thin films of tin sulfide doped lead sulfide (SnS:PbS). In-situ synthesis route using... -
A DFT Study on the Thermal Aryl Migration in Aryliodonium Ylides. Support for...
A DFT study on the intramolecular thermal phenyl migration in iodonium ylides supports a concerted mechanism. In contrast to the two, different than each other, suggested... -
Effect of 2,6-Disubstituted Aryl Groups on Acyclic Conformation: Preference ...
Multiple X-ray crystallographic and 1H NMR spectroscopic studies demonstrate that 2,6-disubstituted aryl groups exert a strong effect on acyclic conformation, inducing the... -
Solid-Phase Synthesis of Bis-2-imidazolidinethiones from Resin-Bound Tripeptides
The exhaustive reduction of resin-bound tripeptides with borane afforded three secondary amines and one primary amine. The treatment of the solid-support polyamines with...
