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Effect of a 17α-(3-Hydroxypropyl)-17β-acetyl Substituent Pattern on the Gluco...
Replacing the 17α-acetoxy substituent in an antiprogestational 17β-acetyl-11β-arylestra-4,9-dien-3-one by 3-hydroxypropyl significantly diminished glucocorticoid receptor... -
Unusual Transannular Cyclization Products of Sarcophytoxide, a 14-Membered Ma...
Treatment of sarcophytoxide with trimethylsilyl trifluoromethanesulfonate afforded an aromatic ketone as an unusual cyclization product. The modified Mosher's method and X-ray... -
Preparation and unequivocal identification of the regioisomers of nitrocatech...
ABSTRACTThe four positional isomers of nitrocatechol monobenzyl ether were prepared as intermediates to nitrobenzodioxanes directly from 2-benzyloxyphenol or, through two-four... -
Reactions of α,α‘-Dihydroxy Ketones with Phosgene. Structural Requirements fo...
α,α‘-Dihydroxy ketones having two OH groups that can come into close proximity react with phosgene in the presence of DMAP to produce 1,3-dioxane-2,5-diones. When covalent... -
Enantioselective Epoxidation of Terminal Olefins by Chiral Dioxirane
This paper describes an enantioselective epoxidation of terminal olefins using chiral ketone 3 as catalyst and Oxone as oxidant. Up to 85% ee has been obtained. -
Profilin 2 promotes migration, invasion, and stemness of HT29 human colorecta...
We investigated the role of profilin 2 in the stemness, migration, and invasion of HT29 cancer stem cells (CSCs). Increased and decreased levels of profilin 2 significantly... -
Application of Stereoselective Ether Transfer to the Synthesis of Isotactic P...
An efficient, convergent synthetic strategy has been developed which enables the synthesis of a series of naturally occurring isotactic polymethoxy compounds. Ether transfer... -
Synthesis of Seven-Membered Cyclic Enol Ether Derivatives from the Reaction o...
The tandem Michael−intramolecular Wittig reactions of a five-membered cyclic phosphonium ylide (2) with α,β-unsaturated esters afforded seven-membered cyclic enol ether... -
Absolute Configuration of Brevisamide and Brevisin: Confirmation of a Univers...
The discovery of brevisin, the first example of an “interrupted” polycyclic ether, obtained from the dinoflagellate Karenia brevis, posed some important questions regarding the... -
Unusual Cyclization Products Derived from Photolysis of Breslow's Steroidal B...
Unusual Cyclization Products Derived from Photolysis of Breslow's Steroidal Benzophenone Esters -
Photoinduced Electron-Transfer Bicyclopropenyl-benzene Rearrangements of 2,2‘...
The 9,10-dicyanoanthracene-sensitized photoreaction of 1-methyl- and 1,1‘-dimethyl-2,2‘,3,3‘-tetraphenylbicyclopropenyl gives the corresponding benzene and Dewar benzene... -
An Efficient C−H Oxidation Protocol for α-Hydroxylation of Cyclic Steroidal E...
Various C-16 hydroxy steroids have been prepared with the aid of CrO3/Bu4NIO4. Out of the two possible reaction courses, transition state B is favored because of less steric... -
Theoretical Studies on Graphyne Substructures: Geometry, Aromaticity, and El...
The geometries of multiply fused dehydrobenzo[12]annulenes [12]DBAs 2−7 with various topologies, which are considered as graphyne fragments, have been optimized at the... -
New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Applicatio...
Treatment of indole alkaloids with hypervalent iodine in the presence of ethylene glycol provides 2,3-ethylene glycol bridged adducts that could be converted into the original... -
Study on Photochromism of Diarylethenes with a 2,5-Dihydropyrrole Bridging Un...
Symmetric and nonsymmetric diarylethenes with a 2,5-dihydropyrrole bridging unit have been prepared, and the photochromic properties are investigated. Both symmetric and... -
Antiaromaticity in Distal Bisfluorenyl Dications Separated by Multiple Discre...
The effect of spacers on the antiaromaticity of bisfluorenyl dications was examined. For systems such as 4a−c in which extensive delocalization of the positive charge through... -
Reduced Excimer Formation in Polyfluorenes by Introducing Coil-like Poly[pent...
Conjugated polymers are of special interest due to their excellent optical and optoelectrical properties both in the solid state and in selective solvents. They have... -
Microwave-Assisted Allylation of Acetals with Allyltrimethylsilane in the Pre...
We describe the first synthesis of homoallyl ethers from acetals and allyltrimethylsilane using microwave heating and CuBr as a promoter. This method works best for aromatic... -
Unusual Phase Behavior of the Mixture of Poly(acrylic acid) and Poly(diallyld...
A new type of temperature-sensitive polymer systems based on mixtures of poly(acrylic acid) (PAA) and poly(diallyldimethylammonium chloride) (PDADMAC) in strongly acidic aqueous... -
Synthesis of Optically Active Vicinal Fluorohydrins by Lipase-Catalyzed Derac...
Three microbial lipases have been used to deracemize trans-2-fluorocycloalkanols 2 both by hydrolysis of the corresponding acetates 3 or chloroacetates 4 and by esterification...
