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Effect of a 17α-(3-Hydroxypropyl)-17β-acetyl Substituent Pattern on the Gluco...
Replacing the 17α-acetoxy substituent in an antiprogestational 17β-acetyl-11β-arylestra-4,9-dien-3-one by 3-hydroxypropyl significantly diminished glucocorticoid receptor... -
Unusual Transannular Cyclization Products of Sarcophytoxide, a 14-Membered Ma...
Treatment of sarcophytoxide with trimethylsilyl trifluoromethanesulfonate afforded an aromatic ketone as an unusual cyclization product. The modified Mosher's method and X-ray... -
Enantioselective Epoxidation of Terminal Olefins by Chiral Dioxirane
This paper describes an enantioselective epoxidation of terminal olefins using chiral ketone 3 as catalyst and Oxone as oxidant. Up to 85% ee has been obtained. -
Absolute Configuration of Brevisamide and Brevisin: Confirmation of a Univers...
The discovery of brevisin, the first example of an “interrupted” polycyclic ether, obtained from the dinoflagellate Karenia brevis, posed some important questions regarding the... -
Unusual Cyclization Products Derived from Photolysis of Breslow's Steroidal B...
Unusual Cyclization Products Derived from Photolysis of Breslow's Steroidal Benzophenone Esters -
Photoinduced Electron-Transfer Bicyclopropenyl-benzene Rearrangements of 2,2‘...
The 9,10-dicyanoanthracene-sensitized photoreaction of 1-methyl- and 1,1‘-dimethyl-2,2‘,3,3‘-tetraphenylbicyclopropenyl gives the corresponding benzene and Dewar benzene... -
An Efficient C−H Oxidation Protocol for α-Hydroxylation of Cyclic Steroidal E...
Various C-16 hydroxy steroids have been prepared with the aid of CrO3/Bu4NIO4. Out of the two possible reaction courses, transition state B is favored because of less steric... -
Theoretical Studies on Graphyne Substructures: Geometry, Aromaticity, and El...
The geometries of multiply fused dehydrobenzo[12]annulenes [12]DBAs 2−7 with various topologies, which are considered as graphyne fragments, have been optimized at the... -
New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Applicatio...
Treatment of indole alkaloids with hypervalent iodine in the presence of ethylene glycol provides 2,3-ethylene glycol bridged adducts that could be converted into the original... -
Study on Photochromism of Diarylethenes with a 2,5-Dihydropyrrole Bridging Un...
Symmetric and nonsymmetric diarylethenes with a 2,5-dihydropyrrole bridging unit have been prepared, and the photochromic properties are investigated. Both symmetric and... -
Antiaromaticity in Distal Bisfluorenyl Dications Separated by Multiple Discre...
The effect of spacers on the antiaromaticity of bisfluorenyl dications was examined. For systems such as 4a−c in which extensive delocalization of the positive charge through... -
Reduced Excimer Formation in Polyfluorenes by Introducing Coil-like Poly[pent...
Conjugated polymers are of special interest due to their excellent optical and optoelectrical properties both in the solid state and in selective solvents. They have... -
Unusual Phase Behavior of the Mixture of Poly(acrylic acid) and Poly(diallyld...
A new type of temperature-sensitive polymer systems based on mixtures of poly(acrylic acid) (PAA) and poly(diallyldimethylammonium chloride) (PDADMAC) in strongly acidic aqueous... -
Synthesis of Optically Active Vicinal Fluorohydrins by Lipase-Catalyzed Derac...
Three microbial lipases have been used to deracemize trans-2-fluorocycloalkanols 2 both by hydrolysis of the corresponding acetates 3 or chloroacetates 4 and by esterification... -
The Solid-Phase Zincke Reaction: Preparation of ω-Hydroxy Pyridinium Salts i...
A study of structural modifications of MPB-07 was undertaken as part of a synthetic program aimed at discovering small molecules with CFTR activation potential. Solid-phase... -
(Triphenyl phosphite)gold(I)-Catalyzed Intermolecular Hydroamination of Alken...
Intermolecular addition of different sulfonamides to alkenes and conjugated dienes can be carried out using a low loading of (triphenyl phosphite)gold(I) chloride and silver... -
Computational DFT Investigation of Vicinal Amide Group Anchimeric Assistance ...
Density functional theory (DFT) computations in solvent have been used to investigate the mechanism of anchimeric assistance (by a vicinal amide group) in the acid-induced ether... -
Mechanism of Metal Chloride-Promoted Mukaiyama Aldol Reactions
Ab initio calculations (MP2/6-311+G*//B3LYP/6-31G) were employed to investigate the mechanism of metal chloride-promoted Mukaiyama aldol reaction between trihydrosilyl enol... -
Design of Biocompatible Dendrimers with Environment Sensitivity
Design of Biocompatible Dendrimers with Environment Sensitivity
