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Unusual Transannular Cyclization Products of Sarcophytoxide, a 14-Membered Ma...
Treatment of sarcophytoxide with trimethylsilyl trifluoromethanesulfonate afforded an aromatic ketone as an unusual cyclization product. The modified Mosher's method and X-ray... -
Preparation and unequivocal identification of the regioisomers of nitrocatech...
ABSTRACTThe four positional isomers of nitrocatechol monobenzyl ether were prepared as intermediates to nitrobenzodioxanes directly from 2-benzyloxyphenol or, through two-four... -
Reactions of α,α‘-Dihydroxy Ketones with Phosgene. Structural Requirements fo...
α,α‘-Dihydroxy ketones having two OH groups that can come into close proximity react with phosgene in the presence of DMAP to produce 1,3-dioxane-2,5-diones. When covalent... -
Profilin 2 promotes migration, invasion, and stemness of HT29 human colorecta...
We investigated the role of profilin 2 in the stemness, migration, and invasion of HT29 cancer stem cells (CSCs). Increased and decreased levels of profilin 2 significantly... -
Application of Stereoselective Ether Transfer to the Synthesis of Isotactic P...
An efficient, convergent synthetic strategy has been developed which enables the synthesis of a series of naturally occurring isotactic polymethoxy compounds. Ether transfer... -
Theoretical Studies on Graphyne Substructures: Geometry, Aromaticity, and El...
The geometries of multiply fused dehydrobenzo[12]annulenes [12]DBAs 2−7 with various topologies, which are considered as graphyne fragments, have been optimized at the... -
New Procedure to Mask the 2,3-π Bond of the Indole Nucleus and Its Applicatio...
Treatment of indole alkaloids with hypervalent iodine in the presence of ethylene glycol provides 2,3-ethylene glycol bridged adducts that could be converted into the original... -
Reduced Excimer Formation in Polyfluorenes by Introducing Coil-like Poly[pent...
Conjugated polymers are of special interest due to their excellent optical and optoelectrical properties both in the solid state and in selective solvents. They have... -
Microwave-Assisted Allylation of Acetals with Allyltrimethylsilane in the Pre...
We describe the first synthesis of homoallyl ethers from acetals and allyltrimethylsilane using microwave heating and CuBr as a promoter. This method works best for aromatic... -
Synthesis of Optically Active Vicinal Fluorohydrins by Lipase-Catalyzed Derac...
Three microbial lipases have been used to deracemize trans-2-fluorocycloalkanols 2 both by hydrolysis of the corresponding acetates 3 or chloroacetates 4 and by esterification... -
The Solid-Phase Zincke Reaction: Preparation of ω-Hydroxy Pyridinium Salts i...
A study of structural modifications of MPB-07 was undertaken as part of a synthetic program aimed at discovering small molecules with CFTR activation potential. Solid-phase... -
(Triphenyl phosphite)gold(I)-Catalyzed Intermolecular Hydroamination of Alken...
Intermolecular addition of different sulfonamides to alkenes and conjugated dienes can be carried out using a low loading of (triphenyl phosphite)gold(I) chloride and silver... -
Design of Biocompatible Dendrimers with Environment Sensitivity
Design of Biocompatible Dendrimers with Environment Sensitivity -
Thiacrown Ether Technology in Lipase-Catalyzed Reaction: Scope and Limitatio...
Both reaction rate and enantioselectivity in Pseudomonas cepacia lipase (PCL)-catalyzed hydrolysis of 3-hydroxyalkanenitrile acetates were significantly changed by the addition... -
Direct Electroreductive Preparation of Indolines and Indoles from Diazonium S...
Indolines and indoles are prepared for the first time by direct electrochemical reduction of arenediazonium salts. -
Mechanistic Studies of the tRNA-Modifying Enzyme QueA: A Chemical Imperative...
The enzyme S-adenosylmethionine:tRNA ribosyltransferase-isomerase (QueA) catalyzes the penultimate step in the biosynthesis of the tRNA nucleoside queuosine, a unique ribosyl... -
MALDI-TOF Analysis of Dendrimer-like Poly(ethylene oxide)s
MALDI-TOF Analysis of Dendrimer-like Poly(ethylene oxide)s -
Solid-Phase Preparation of Dienes
The Stille reaction has been used to prepare a variety of functionalized dienes on a solid support.
