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Discovery of 1-(4-Methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,...
Efforts to identify a suitable follow-on compound to razaxaban (compound 4) focused on modification of the carboxamido linker to eliminate potential in vivo hydrolysis to a... -
dedup_wf_001--6a72594ea900de3929241813a2954b20
Lightning talk presented at Collaborations Workshop 2019 organised by the Software Sustainability Institute. -
<i>N</i>-Phenylphenylglycines as Novel Corticotropin Releasing Factor Recepto...
Screening of a computationally designed synthetic library led to the discovery of the N-phenylphenylglycines (NPPGs) as a novel class of human corticotropin releasing factor... -
Catalytic Carbon−Halogen Bond Activation: Trends in Reactivity, Selectivity,...
We have theoretically studied the oxidative addition of all halomethanes CH3X (with X = F, Cl, Br, I, At) to Pd and PdCl-, using both nonrelativistic and... -
r37980778c78--56fcee8741a21a8729fa2db393bd30b0
Design, synthesis, and in vitro bioevaluation of a new class of potential dual PPARα and γ agonists discovered through a structure-driven design paradigm are described. The... -
r37980778c78--93183a566ab17aaa0191dac4b12dd679
A Streptavidin−Protein Cage Janus Particle for Polarized Targeting and Modular Functionalization -
Aryl Bridged 1-Hydroxypyridin-2-one: Effect of the Bridge on the Eu(III) Sens...
The efficiency of Eu3+ luminescence by energy transfer from an antenna ligand can be strongly dependent on the metal ion coordination geometry. The geometric component of the... -
Access Control
Publisher Summary Access control is the control of access to property, services, events, or information, and is a combination of several things including control, record... -
Design of Novel Derivatives of Phosphonoformate (Foscarnet) as Prodrugs and A...
Design of Novel Derivatives of Phosphonoformate (Foscarnet) as Prodrugs and Antiviral Agents -
r37980778c78--fe4e83e064bdf00dc834ea490c40288c
A ratiometric fluorescent biosensor for Hg2+ is constructed from the MerR protein and a duplex DNA containing a pyrene excimer. -
Discovery of Potent 3,5-Diphenyl-1,2,4-oxadiazole Sphingosine-1-phosphate-1 (...
A class of 3,5-diphenyl-1,2,4-oxadiazole based compounds have been identified as potent sphingosine-1-phosphate-1 (S1P1) receptor agonists with minimal affinity for the S1P2 and... -
Dehydrogenation Promotion of LiBH<sub>4</sub>·NH<sub>3</sub> Through Heating ...
Amminelithium borohydride (LiBH4·NH3) is one of the most hydrogen-rich inorganic materials, showing potential application for hydrogen storage. In this paper, the... -
Inherently Chiral Biscalix[4]arenes: Design and Syntheses
Inherently chiral biscalix[4]arenes have been designed and synthesized by covalently assembling two calix[4]arene building blocks in a 1,3-position linking with 1,2-position... -
(PDF) Halki Diabetes Remedy Review: Eric Whitfield
Product Name: Halki Diabetes Remedy Creator Name: Eric Whitfield Bonus: Yes Official Website: Click Here Eric Whitfield’s Halki Diabetes Remedy is a 21-days of 60-second... -
Metal−Metal Multiple Bonds in Early/Late Heterobimetallics Support Unusual Tr...
Reduction of Zr/Co heterobimetallic complexes ICo(MesNPiPr2)3ZrCl (1) and ICo(iPrNPiPr2)3ZrCl (2) with excess Na/Hg under N2, followed by subsequent benzene extraction to remove... -
Lipidome improves predictive ability of subclinical atherosclerosis over trad...
Background: Early detection of atherosclerotic process is crucial for primary prevention of cardiovascular diseases. In this study we tested independent and added predictive... -
1,2,4-Triazol-3-yl-thiopropyl-tetrahydrobenzazepines: A Series of Potent and...
The discovery of new highly potent and selective dopamine D3 receptor antagonists has recently permitted characterization of the role of the dopamine D3 receptor in a wide range... -
r37980778c78--45c77806280e278526960e808d2b7b2b
Electrolysis of benzylthiocyanate, benzyl chloride, p-methylbenzyl chloride, p-methoxybenzyl chloride, or toluene in acetonitrile, at platinum electrodes in a two compartments... -
Inhibition of gap junctional intercellular communication by toxic metals
As metals are ubiquitous in the environment, humans are continuously exposed to them. Although some metallic ions play key roles in human physiology, most metals are redundant... -
r37980778c78--566516baee56754d67c275c2225a172b
We previously prepared the oligonucleotides (ODNs) conjugated to an anthraquinone (AQ) group via one carbon linker at the 2′-sugar position. When these modified ODNs bind to...
