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Oxidative stress and premature senescence in corneal endothelium following pe...
Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,... -
Adherence to guidelines across different specialties to prevent infections in...
Abstract Background Substantial numbers of patients are now receiving either immunosuppressive therapies or chemotherapy. There are significant risks in such patients of... -
IgG4-related aortitis/periaortitis and periarteritis: a distinct spectrum of ...
Abstract Background Large vessels could be involved in immunoglobulin (Ig)-G4-related disease (IgG4-RD). This study aimed to clarify the clinical features and evaluate the... -
Hemodynamic impacts of flow diverter devices on the ophthalmic artery
Abstract Background Flow diverter devices are increasingly used for endovascular treatment of internal carotid artery aneurysms. Treatment of ophthalmic segment aneurysms with... -
A novel pyruvate kinase and its application in lactic acid production under o...
Abstract Background Pyruvate kinase (Pyk) catalyzes the generation of pyruvate and ATP in glycolysis and functions as a key switch in the regulation of carbon flux distribution.... -
Parental concerns and uptake of childhood vaccines in rural Tanzania – a mixe...
Abstract Background Vaccine hesitancy has been recognized as an important barrier to timely vaccinations around the world, including in sub-Saharan Africa. In Tanzania, 1 in 4... -
Low birth weight among term newborns in Wolaita Sodo town, South Ethiopia: a ...
Abstract Background In low income countries, many low birth weight newborns often miss the chance for survival sooner or later. Others who survive would also face increased... -
Non-malaria fevers in a high malaria endemic area of Ghana
Abstract Background The importance of fevers not due to malaria [non–malaria fevers, NMFs] in children in sub-Saharan Africa is increasingly being recognised. We have... -
Which patients benefit from physical activity on prescription (PAP)? A prospe...
Abstract Background There is robust evidence that regular physical activity (PA) has positive health effects. However, the best PA methods and the most important correlates for... -
Delay in tuberculosis diagnosis and treatment in Amhara state, Ethiopia
Abstract Background Delayed presentation is a major problem contributing to the high burden and transmission of tuberculosis (TB) in developing countries. The delay may be due... -
Determinants of patient and health care services delays for tuberculosis diag...
Abstract Background Prompt diagnosis of active tuberculosis (TB) has paramount importance to reduce TB morbidity and mortality and to prevent the spread of Mycobacterium... -
Husbands involvement in birth preparedness and complication readiness in Axum...
Abstract Background Worldwide, around 289,000 maternal mortalities occur each year from complications related to pregnancy and childbirth. In Ethiopia, the maternal mortality... -
Increased risk of maternal and neonatal complications in hormone replacement ...
Abstract Background The endometrial preparation during frozen embryo transfer (FET) can be performed by natural cycle (NC), hormone replacement therapy (HRT) cycle and cycle... -
Risk factors, costs and complications of delayed hospital discharge from inte...
Abstract Background Hospitalized patients are designated alternate level of care (ALC) when they no longer require hospitalization but discharge is delayed while they await... -
Patient and health system delays before registration among migrant patients w...
Abstract Background Early diagnosis and treatment is vital for effective tuberculosis (TB) management especially among migrant populations who are a vulnerable group. We aimed... -
Hyponatremia is a marker of disease severity in HIV-infected patients: a retr...
Abstract Background Hyponatremia is a frequent electrolyte disorder in HIV-infected patients with a prevalence of up to 56% in the pre-cART era. Several studies have... -
Gum Arabic as fetal hemoglobin inducing agent in sickle cell anemia; in vivo ...
Abstract Background High levels of fetal haemoglobin (HbF) decrease sickle cell anaemia (SCA) severity and leads to improved survival. According to in vivo and in vitro studies,... -
Caffeine exposure during pregnancy, small for gestational age birth and neona...
Abstract Background Maternal caffeine intake has repeatedly been linked to babies being born small for gestational age (SGA). SGA babies are known to be at increased risk for... -
A lactate-targeted resuscitation strategy may be associated with higher morta...
Abstract Background Capillary refill time (CRT) may improve more rapidly than lactate in response to increments in systemic flow. Therefore, it can be assessed more frequently... -
Use of meat juice and blood serum with a miniaturised protein microarray assa...
Abstract Background Serological screening of pig herds at the abattoir is considered a potential tool to improve meat inspection procedures and herd health management....