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Lytic polysaccharide monooxygenases and other oxidative enzymes are abundantl...
Abstract Background Starch is the second most abundant plant-derived biomass and a major feedstock in non-food industrial applications and first generation biofuel production.... -
ERα-36 regulates progesterone receptor activity in breast cancer
Abstract Background Alterations in estrogen and progesterone signaling, via their respective receptors, estrogen receptor alpha (ERα) and progesterone receptor (PR),... -
The effects of green cardamom on blood glucose indices, lipids, inflammatory ...
Abstract Background The relationship between dietary components and nonalcoholic fatty liver disease (NAFLD) needs to be further investigated. The potential health benefits of... -
Supplement of microbiota-accessible carbohydrates prevents neuroinflammation ...
Abstract Background Western pattern diets induce neuroinflammation and impair cognitive behavior in humans and animals. Neuroinflammation and cognitive impairment have been... -
Untargeted metabolomics reveals the effect of lovastatin on steroid-induced n...
Abstract Purpose Lovastatin is an important medicine and it shows a significant effect against glucocorticoid-induced necrosis of the femoral head. This study aimed to... -
Additional file 1: of The prominent alteration in transcriptome and metabolom...
Table S1. The complete list of differentially expressed genes in control and VB1-treated samples. (XLS 111 kb) -
Development of a high-throughput screen to identify small molecule enhancers ...
Abstract Background Duchenne muscular dystrophy (DMD) is caused by loss of sarcolemma connection to the extracellular matrix. Transgenic overexpression of the transmembrane... -
The Ussing chamber system for measuring intestinal permeability in health and...
Abstract Background The relationship between intestinal epithelial integrity and the development of intestinal disease is of increasing interest. A reduction in mucosal... -
Deciphering how LIP2 and POX2 promoters can optimally regulate recombinant pr...
Abstract Background In recent years, the non-conventional model yeast species Yarrowia lipolytica has received much attention because it is a useful cell factory for producing... -
Air pollution-induced placental epigenetic alterations in early life: a candi...
Particulate matter (PM) exposure during in utero life may entail adverse health outcomes in later-life. Air pollution's adverse effects are known to alter gene expression... -
Wnt5a-induced M2 polarization of tumor-associated macrophages via IL-10 promo...
Abstract Background Tumor-associated macrophages (TAMs) in the tumor microenvironment influence tumor initiation, invasion and metastasis. Several studies have shown that Wnt5a... -
MicroRNA-181a as novel liquid biopsy marker of central nervous system involve...
Abstract Background Refractory central nervous system (CNS) involvement is among the major causes of therapy failure in childhood acute leukemia. Applying contemporary... -
Simvastatin and a Plant Galactolipid Protect Animals from Septic Shock by Reg...
Abstract Sepsis remains a major medical issue despite decades of research. Identification of important inflammatory cascades and key molecular mediators are crucial for... -
Thrombin-induced, TNFR-dependent miR-181c downregulation promotes MLL1 and NF...
Abstract Background Controlling thrombin-driven microglial activation may serve as a therapeutic target for intracerebral hemorrhage (ICH). Here, we investigated microRNA... -
In utero exposure to ultrafine particles promotes placental stress-induced pr...
Abstract Background Exposure to particulate matter (PM) is associated with an adverse intrauterine environment, which can promote adult cardiovascular disease (CVD) risk.... -
A pilot study of essential tremor: cerebellar GABA+/Glx ratio is correlated w...
Abstract Objective Essential tremor is a common movement disorder with an unclear origin. Emerging evidence suggests the role of the cerebellum and the thalamus in tremor... -
Maternal and cord blood adiponectin levels in relation to post-natal body siz...
Abstract Background Adiponectin is an adipocyte hormone involved in energy homeostasis and metabolism. However, its role in early infancy is poorly understood. Methods We... -
Evaluation of human primary intestinal monolayers for drug metabolizing capab...
Abstract Background The intestinal epithelium is a major site of drug metabolism in the human body, possessing enterocytes that house brush border enzymes and phase I and II... -
Sensitization profile in patients with respiratory allergic diseases: differe...
Abstract Background Component-resolved diagnosis (CRD) allows to identify single molecular allergen components, and constitutes a routine practice in many allergy units.... -
Inhibitory effects of aspirin-triggered resolvin D1 on spinal nociceptive pro...
Abstract Background Harnessing the actions of the resolvin pathways has the potential for the treatment of a wide range of conditions associated with overt inflammatory...
