576 items found

Licenses: License Not Specified Tags: Genetics Medicine Physiology Groups: figshare Types: other

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    MRI of trunk muscles and motor and respiratory function in patients with myot...

    Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to...
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    Perioperative cerebrospinal fluid and plasma inflammatory markers after ortho...

    Abstract Background Postoperative delirium is prevalent in older patients and associated with worse outcomes. Recent data in animal studies demonstrate increases in inflammatory...
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    Sedentary behavior patterns and adiposity in children: a study based on compo...

    Abstract Background Between-person differences in sedentary patterns should be considered to understand the role of sedentary behavior (SB) in the development of childhood...
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    Eye Biometry Using Quantitatve 3-D OCT

    Cataracts cause the crystalline lens of the eye to progressively lose its transparency, which decreases vision. It is one of the major causes of vision loss in our aging...
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    Involvement of ABC-transporters and acyltransferase 1 in intracellular choles...

    Abstract Background Understanding pathogenic mechanisms is imperative for developing novel treatment to the tuberculosis, an important public health burden worldwide. Recent...
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    Omalizumab in patients with severe asthma and persistent sputum eosinophilia

    Abstract Omalizumab, a recombinant humanized monoclonal antibody targeting the IgE molecule, is the first biologic approved for moderate-to-severe allergic asthmatics, who...
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    Pleural effusion from intrathoracic migration of a ventriculo-peritoneal shun...

    Abstract Background Pleural effusion is a rare complication of ventriculo-peritoneal (VP) cerebrospinal fluid (CSF) shunting and its diagnosis is difficult in patients with...
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    Effects of Text-to-Speech Software Use on the Reading Proficiency of High Sch...

    Effects of Text-to-Speech Software Use on the Reading Proficiency of High School Struggling Readers
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    Effects of very early start of norepinephrine in patients with septic shock: ...

    Abstract Background Optimal timing for the start of vasopressors (VP) in septic shock has not been widely studied since it is assumed that fluids must be administered in...
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    Autonomic nervous system response to remote ischemic conditioning: heart rate...

    Abstract Background Remote ischemic conditioning (RIC) is a procedure applied in a limb for triggering endogenous protective pathways in distant organs, namely brain or heart....
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    Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-indu...

    Abstract Background Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection...
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    Associations Between Practice-Related Changes in Motor Performance and Muscle...

    Abstract Background A well-learned motor skill is characterized by the efficient activation of muscles that are involved in movement execution. However, it is unclear if...
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    Correlates of knee bone marrow lesions in younger adults

    Abstract Background Subchondral bone marrow lesions (BMLs) play a key role in the pathogenesis of osteoarthritis (OA) and are associated with pain and structural progression in...
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    Cluster-randomized, controlled evaluation of a teacher led multi factorial sc...

    Abstract Background The aim of this cluster-randomised, controlled study was to examine whether a teacher-led multifactorial back education programme could improve back pain in...
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    Comparative analyses of the in vivo induction and transmission of α-synuclein...

    Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central...
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    Nanomedicine-driven neuropathic pain relief in a rat model is associated with...

    Abstract We explored the immune neuropathology underlying multi-day relief from neuropathic pain in a rat model initiated at the sciatic nerve, by using a nanoemulsion-based...
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    Perioperative statin therapy in cardiac and non-cardiac surgery: a systematic...

    Abstract Background The effects of perioperative statin therapy on clinical outcome after cardiac or non-cardiac surgery are controversial. We aimed to assess the association...
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    Dexketoprofen/tramadol 25 mg/75 mg: randomised double-blind trial in moderate...

    Abstract Background Dexketoprofen trometamol plus tramadol hydrochloride is a new oral combination of two analgesics, which have different mechanisms of action for the treatment...
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    The whole - genome expression analysis of peripheral blood mononuclear cells ...

    Abstract Background Up to 30 % of adults with severe asthma are hypersensitive to aspirin and no unambiguous theory exists which provides a satisfactory explanation for the...
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    Differential expression of E-type prostanoid receptors 2 and 4 in microglia s...

    Abstract Background Cyclooxygenase-2 (COX-2) is induced under inflammatory conditions, and prostaglandin E2 (PGE2) is one of the products of COX activity. PGE2 has pleiotropic...