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Licenses: License Not Specified Tags: Developmental Biology Physiology Science Policy Groups: figshare Types: other

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    Analysis of survival after initiation of continuous renal replacement therapy...

    Abstract Background No study has specifically investigated the duration of continuous renal replacement therapy (CRRT) in patients who experienced acute kidney injury during...
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    MRI of trunk muscles and motor and respiratory function in patients with myot...

    Abstract Background Myotonic Dystrophy 1 (DM1) causes progressive myopathy of extremity muscles. DM1 may also affect muscles of the trunk. The aim of this study was to...
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    Pleural effusion from intrathoracic migration of a ventriculo-peritoneal shun...

    Abstract Background Pleural effusion is a rare complication of ventriculo-peritoneal (VP) cerebrospinal fluid (CSF) shunting and its diagnosis is difficult in patients with...
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    Characterization of a thalamic nucleus mediating habenula responses to change...

    Abstract Background Neural activity in the vertebrate habenula is affected by ambient illumination. The nucleus that links photoreceptor activity with the habenula is not well...
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    Effects of the Toll-like receptor 7 (TLR7) agonist, AZD8848, on allergen-indu...

    Abstract Background Although allergic asthma is a complex area with many interacting factors involved, the ‘hygiene hypothesis’ proposes that a lack of exposure to infection...
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    How to deal with a temporary suspension and restarting your trial: our experi...

    Abstract Whilst the issues around early termination of randomised controlled trials (RCTs) are well documented in the literature, trials can also be temporarily suspended with...
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    Eye irritation testing of nanomaterials using the EpiOcular™ eye irritation t...

    Abstract Background Assessment of eye irritation hazard has long been a core requirement in any chemical legislation. Nevertheless, publications focussing on the eye damaging...
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    Sex hormones affect endothelial lipase-mediated lipid metabolism and atherosc...

    Abstract Background Endothelial lipase (EL) plays an important role in lipoprotein metabolism and atherosclerosis. To study the functional roles of EL, we recently generated...
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    Genes targeted by the Hedgehog-signaling pathway can be regulated by Estrogen...

    Abstract Background Nuclear receptor family member, Estrogen related receptor β, and the Hedgehog signal transduction pathway are both reported to relate to tumorigenesis and...
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    Sensor-based characterization of daily walking: a new paradigm in pre-frailty...

    Abstract Background Frailty is a highly recognized geriatric syndrome resulting in decline in reserve across multiple physiological systems. Impaired physical function is one of...
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    Unique patterns of lower respiratory tract microbiota are associated with inf...

    Abstract Background The lung microbiome maintains the homeostasis of the immune system within the lungs. In acute respiratory distress syndrome (ARDS), the lung microbiome is...
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    Vasoresponsiveness in patients with heart failure (VASOR): protocol for a pro...

    Abstract Background Vasoplegia is a severe complication which may occur after cardiac surgery, particularly in patients with heart failure. It is a result of activation of...
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    The whole - genome expression analysis of peripheral blood mononuclear cells ...

    Abstract Background Up to 30 % of adults with severe asthma are hypersensitive to aspirin and no unambiguous theory exists which provides a satisfactory explanation for the...
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    Resveratrol mediates mechanical allodynia through modulating inflammatory res...

    Abstract Background Neuropathic pain (NeuP) is a chronic and challenging clinical problem, with little effective treatment. Resveratrol has shown neuroprotection by inhibiting...
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    Periostin involved in the activated hepatic stellate cells-induced progressio...

    Abstract Background Incomplete thermal ablation may induce invasiveness of hepatocellular carcinoma (HCC). Here, we investigated whether activated hepatic stellate cells (HSCs)...
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    Lytic polysaccharide monooxygenases and other oxidative enzymes are abundantl...

    Abstract Background Starch is the second most abundant plant-derived biomass and a major feedstock in non-food industrial applications and first generation biofuel production....
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    Quantitative evaluation of corneal epithelial edema after cataract surgery us...

    Abstract Purpose The optical density of the cornea can be evaluated quantitatively by “densitometry” using a rotating Scheimpflug camera. Densitometry allows evaluation of...
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    Minification of fundus optical coherence tomographic images in gas-filled eye

    Abstract Background Optical coherence tomography (OCT) is being used increasingly to evaluate and manage a variety of retinal diseases, but not much is known about the...
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    Evaluation of EMG pattern recognition for upper limb prosthesis control: a ca...

    Abstract Background Although electromyogram (EMG) pattern recognition (PR) for multifunctional upper limb prosthesis control has been reported for decades, the clinical benefits...
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    Gout and sexual function: patient perspective of how gout affects personal re...

    Abstract Background In absence of previous studies, we assessed how gout impacts relationship and intimacy with spouse/significant other. Methods We enrolled a convenience...