576 items found

Licenses: License Not Specified Tags: Genetics Medicine Physiology Groups: figshare Types: other

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    Clinical factors associated with the recovery of cardiovascular autonomic neu...

    Abstract Background Cardiovascular autonomic neuropathy (CAN) is a major cause of morbidity and mortality in diabetes patients. Although several risk factors for CAN progression...
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    Assessment of eye length changes in accommodation using dynamic extended-dept...

    It has been suggested that accommodation induces increases in axial eye length which could contribute to the development of myopia. However, it is debated whether changes in eye...
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    Sprifermin (rhFGF18) modulates extracellular matrix turnover in cartilage exp...

    Abstract Background Sprifermin (recombinant human fibroblast growth factor 18) is in clinical development as a potential disease-modifying osteoarthritis drug (DMOAD). In vitro...
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    Cohort study on living arrangements of older men and women and risk for basic...

    Abstract Background Living arrangements of older adults have changed worldwide with increasing solitary and non-spouse households, which could affect social care systems....
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    Isolated unilateral temporalis muscle hypertrophy in a child: a case report w...

    Abstract Background Temporalis muscle hypertrophy is a rare entity of masticatory muscle hypertrophy. All types of masticatory muscle hypertrophies have been documented of which...
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    The association between subjective assessment of menstrual bleeding and measu...

    Abstract Background Both iron deficiency and iron deficiency anemia are common in the United States with a prevalence amongst women of 12 % and 4 % respectively. These numbers...
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    Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia

    Abstract Background Hypoxic pulmonary vasoconstriction (HPV) optimizes the match between ventilation and perfusion in the lung by reducing blood flow to poorly ventilated...
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    Obstructive accessory mitral valve tissue in an adult patient: a case report

    Abstract Background Accessory mitral valve tissue is a rare congenital anomaly that is commonly diagnosed in early childhood and rarely in adulthood. It is usually asymptomatic....
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    The impact of frailty and sarcopenia on postoperative outcomes in older patie...

    Abstract Background Gastric cancer is a major health problem, and frailty and sarcopenia will affect the postoperative outcomes in older people. However, there is still no...
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    Type 2 diabetes and cardiometabolic risk may be associated with increase in D...

    Abstract Background Subclinical hypercortisolism and hypothalamic-pituitary-adrenal (HPA) axis dysfunction are associated with type 2 diabetes (T2DM), cardiovascular disease,...
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    Does growth hormone supplementation improve oocyte competence and IVF outcome...

    Abstract Background Many studies have demonstrated the benefits of the addition of growth hormone (GH) to the controlled ovarian stimulation protocol in vitro fertilization...
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    Randomized controlled studies on the efficacy of antiarthritic agents in inhi...

    Abstract Background As an initial step in the development of a local therapeutic to treat osteoarthritis (OA), a number of agents were tested for their ability to block...
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    Heritabilities for the puppy weight at birth in Labrador retrievers

    Abstract Background Weight at birth is an important predictor of neonatal mortality and morbidity in dogs. In addition, the birthweight of the puppies in a litter influences the...
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    Leptin receptor signaling is required for high-fat diet-induced atrophic gast...

    Abstract Background Obesity increases the risk for malignancies in various tissues including the stomach. Atrophic gastritis with precancerous lesions is an obesity-associated...
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    Neuropsychological profiles of adult bipolar disorder patients with and witho...

    Abstract Background Comorbid attention-deficit/hyperactivity disorder (ADHD) is common in bipolar disorder and associated with worse outcomes. Cognitive testing might be a tool...
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    Developmental basis for intestinal barrier against the toxicity of graphene o...

    Abstract Background Intestinal barrier is crucial for animals against translocation of engineered nanomaterials (ENMs) into secondary targeted organs. However, the molecular...