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Patternable particle microarray utilizing controllable particle delivery
Abstract In this study, we demonstrate an on-demand delivering and sequential arraying of single microparticles utilizing multiple pneumatic pressure-driven elastomer valves and... -
One–shot phase stepping with a pulsed laser and modulation of polarization: a...
For applications involving time varying optical phase distributions, fast cameras and/or pulsed lasers have to be used. To apply phase–shifting interferometry techniques (PSI)... -
Fat mass and fat distribution are associated with low back pain intensity and...
Abstract Background Determining the association between body composition and low back pain (LBP) will improve our understanding of the mechanisms by which obesity affects LBP,... -
A novel transcription factor specifically regulates GH11 xylanase genes in Tr...
Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the... -
Three-dimensional Dammann array
We demonstrate a scheme that can produce a three-dimensional (3D) focus spot array in a 3D lattice structure, called a 3D Dammann array, in focal region of an objective. This 3D... -
Fecal metatranscriptomics of macaques with idiopathic chronic diarrhea reveal...
Abstract Background Idiopathic chronic diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. Characterized by chronic inflammation of the... -
A toolset of constitutive promoters for metabolic engineering of Rhodosporidi...
Abstract Background Rhodosporidium toruloides is a promising host for the production of bioproducts from lignocellulosic biomass. A key prerequisite for efficient pathway... -
Pan-cancer analysis reveals technical artifacts in TCGA germline variant calls
Abstract Background Cancer research to date has largely focused on somatically acquired genetic aberrations. In contrast, the degree to which germline, or inherited, variation... -
Improving squalene production by enhancing the NADPH/NADP+ ratio, modifying t...
Abstract Background Squalene is currently used widely in the food, cosmetics, and medicine industries. It could also replace petroleum as a raw material for fuels. Microbial... -
Optimization of CRISPR/Cas9 genome editing in cotton by improved sgRNA expres...
Abstract Background When developing CRISPR/Cas9 systems for crops, it is crucial to invest time characterizing the genome editing efficiency of the CRISPR/Cas9 cassettes,... -
Pulse simulations of a mirrored counterpropagating-QPM device
A basic mirrored counterpropagating quasi-phase-matched device is studied with a pulsed input fundamental plane wave using the method of lines and the relaxation method. Several... -
Association between lumbar disc herniation and facet joint osteoarthritis
Abstract Background This study was performed to investigate the association between lumbar disc herniation (LDH) and facet joint osteoarthritis (FJOA) using magnetic resonance... -
Measurable residual disease in multiple myeloma: ready for clinical practice?
Abstract The landscape of multiple myeloma (MM) has changed considerably in the past two decades regarding new treatments, insight into disease biology and innovation in the... -
Development of a strictly regulated xylose-induced expression system in Strep...
Abstract Background Genetic tools including constitutive and inducible promoters have been developed over the last few decades for strain engineering in Streptomyces. Inducible... -
Light-induced gene expression with photocaged IPTG for induction profiling in...
Abstract Background Inducible expression systems are frequently used for the production of heterologous proteins. Achieving maximum product concentrations requires induction... -
In vivo bioluminescence imaging of the spatial and temporal colonization of l...
Abstract Background Lactic acid bacteria (LAB) are major inhabitants and part of the normal microflora of the gastrointestinal tract (GIT) of humans and animals. Despite... -
An efficient modified method for plant leaf lipid extraction results in impro...
Abstract Background Lipidomics plays an important role in understanding plant adaptation to different stresses and improving our knowledge of the genes underlying lipid... -
Chromosomal integration vectors allowing flexible expression of foreign genes...
Abstract Background Campylobacter jejuni is a major cause of human gastroenteritis yet there is limited knowledge of how disease is caused. Molecular genetic approaches are... -
Synthetic control devices for gene regulation in Penicillium chrysogenum
Abstract Background Orthogonal, synthetic control devices were developed for Penicillium chrysogenum, a model filamentous fungus and industrially relevant cell factory. In the... -
Efficient and mild swern oxidation using a new sulfoxide and <i>bis</i>(trich...
A new type of sulfoxide, 4-(2-(2-(methylsulfinyl) ethyl)-4-nitrophenyl)- morpholine (I) was designed and prepared in good yield. Upon the combination of I andbis...
