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Next-generation sequencing analysis of receptor-type tyrosine kinase genes in...
Abstract Background Improvement in genetic characterization of Colon Cancer (CC) patients is required to propose new potential targets, since surgical resection coupled to... -
Lytic polysaccharide monooxygenases and other oxidative enzymes are abundantl...
Abstract Background Starch is the second most abundant plant-derived biomass and a major feedstock in non-food industrial applications and first generation biofuel production.... -
Andrographis paniculata transcriptome provides molecular insights into tissue...
Abstract Background Kalmegh (Andrographis paniculata) has been widely exploited in traditional medicine for the treatment of infectious diseases and health disorders.... -
Module and individual domain deletions of NRPS to produce plipastatin derivat...
Abstract Background Plipastatin, an antifungal lipopeptide, is synthesized by a non-ribosomal peptide synthetase (NRPS) in Bacillus subtilis. However, little information is... -
ERα-36 regulates progesterone receptor activity in breast cancer
Abstract Background Alterations in estrogen and progesterone signaling, via their respective receptors, estrogen receptor alpha (ERα) and progesterone receptor (PR),... -
Highly active promoters and native secretion signals for protein production d...
Abstract Background The filamentous ascomycete Aspergillus niger is used in many industrial processes for the production of enzymes and organic acids by batch and fed-batch... -
Expression of ACE2 and a viral virulence-regulating factor CCN family member ...
Abstract It has been reported that coronavirus disease 2019 (COVID-19) causes not only pneumonia but also systemic inflammations including central nervous system (CNS)... -
The effects of green cardamom on blood glucose indices, lipids, inflammatory ...
Abstract Background The relationship between dietary components and nonalcoholic fatty liver disease (NAFLD) needs to be further investigated. The potential health benefits of... -
Fecal metatranscriptomics of macaques with idiopathic chronic diarrhea reveal...
Abstract Background Idiopathic chronic diarrhea (ICD) is a common cause of morbidity and mortality among juvenile rhesus macaques. Characterized by chronic inflammation of the... -
Supplement of microbiota-accessible carbohydrates prevents neuroinflammation ...
Abstract Background Western pattern diets induce neuroinflammation and impair cognitive behavior in humans and animals. Neuroinflammation and cognitive impairment have been... -
Prediction of advanced colonic neoplasm in symptomatic patients: a scoring sy...
Abstract Background Fast-track colonoscopy to detect patients with colorectal cancer based on high-risk symptoms is associated with low sensitivity and specificity. The aim was... -
Novel insights into salinity-induced lipogenesis and carotenogenesis in the o...
Abstract Background Chromochloris zofingiensis, a freshwater alga capable of synthesizing both triacylglycerol (TAG) and astaxanthin, has been receiving increasing attention as... -
Screening concepts, characterization and structural analysis of microbial-der...
Lipopeptide biosurfactants are surface active biomolecules that are produced by a variety of microorganisms. Microbial lipopeptides have gained the interest of microbiologists,... -
Untargeted metabolomics reveals the effect of lovastatin on steroid-induced n...
Abstract Purpose Lovastatin is an important medicine and it shows a significant effect against glucocorticoid-induced necrosis of the femoral head. This study aimed to... -
Improving squalene production by enhancing the NADPH/NADP+ ratio, modifying t...
Abstract Background Squalene is currently used widely in the food, cosmetics, and medicine industries. It could also replace petroleum as a raw material for fuels. Microbial... -
Occurrence of Blastocystis sp. and Pentatrichomonas hominis in sheep and goat...
Abstract Background Global data regarding the molecular epidemiology of Blastocystis sp. and Pentatrichomonas hominis in sheep and goats are sparse. China has one of the largest... -
Identification of non-conserved residues essential for improving the hydrocar...
Abstract Background Cyanobacteria produce hydrocarbons corresponding to diesel fuels by means of aldehyde-deformylating oxygenase (ADO). ADO catalyzes a difficult and unusual... -
Tango knock-ins visualize endogenous activity of G protein-coupled receptors ...
G protein-coupled receptors (GPCRs) represent a family of seven-pass transmembrane protein receptors whose ligands include neuropeptides and small-molecule neuromodulators such... -
IDAAPM: integrated database of ADMET and adverse effects of predictive modeli...
Abstract Background The disposition of a pharmaceutical compound within an organism, i.e. its Absorption, Distribution, Metabolism, Excretion, Toxicity (ADMET) properties and... -
Additional file 1: of The prominent alteration in transcriptome and metabolom...
Table S1. The complete list of differentially expressed genes in control and VB1-treated samples. (XLS 111 kb)