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Risk factors for poor asthma control and impaired quality of life in a Caribb...
Asthma, a major cause of disability and reduced quality of life, has a high global prevalence and burden of death. Despite the propitious guidelines, a substantial portion of... -
TNFAIP8L2/TIPE2 impairs autolysosome reformation via modulating the RAC1-MTOR...
Macroautophagy/autophagy is an evolutionarily conserved process that involves the selective degradation of cytoplasmic components within lysosomes in response to starvation.... -
Association of tenofovir disoproxil fumarate exposure with chronic kidney dis...
Tenofovir disoproxil fumarate (TDF)-based regimens have been associated with impaired kidney function and loss of bone mineral density among patients living with HIV (PLWH). We... -
Impact of differential and time-dependent autophagy activation on therapeutic...
Activation of macroautophagy/autophagy, a key mechanism involved in the degradation and removal of aggregated proteins, can successfully reverse Huntington disease phenotypes in... -
Expression of ADR-α1, 2 and ADR-β2 in cumulus cell culture of infertile women...
Alpha and beta-adrenoceptors (ADR-α1, 2, and β2) play a regulatory role in the folliculogenesis and steroidogenesis in the ovarian follicles. This study aimed to measure these... -
Molecular mechanism of microRNA-21 promoting Schwann cell proliferation and a...
At present, the functional recovery after nerve injury is not satisfactory in clinical practice. The aim of this study was to explore the molecular mechanism of miR-21 promoting... -
Comparison between insulin degludec/liraglutide treatment and insulin glargin...
ABSTRACTAim: To evaluate the efficacy and adverse effects of IDegLira and IGlarLixi treatment and to perform a comparison between two strategies.Methods: The registration number... -
The New Zealand white rabbit animal model of acute radiation syndrome: hemato...
Animal models that accurately reflect human responses to radiation injury are needed for advanced mechanistic investigation and development of effective therapeutics. The rabbit... -
miR-296-5p inhibits IL-1β-induced apoptosis and cartilage degradation in huma...
Osteoarthritis (OA) is characterized by apoptosis of chondrocytes and an imbalance of extracellular matrix (ECM) synthesis and catabolism. Emerging evidence has demonstrated...
