19 items found

Groups: figshare Open Access Tags: AD Cell Biology Pharmacology Science Policy

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  • dataset

    Demographics and clinical characteristics.

    Values are mean ± standard deviation unless otherwise noted. Categorical data are compared by chi-square tests, two tailed; all other p values are by Student's t test, two tailed.
  • dataset

    Meta-analyses of comparative efficacy of antidepressant medications on periph...

    BackgroundBrain derived neurotrophic factor (BDNF) is one of the most important regulatory proteins in the pathophysiology of major depressive disorder (MDD). Increasing numbers...
  • dataset

    Subjects’ characteristics.

    Δ changes over 12 weeks. BMI, Body Mass Index; FM, fat mass; FFM, fat free mass; PAL, physical activity level. These data concern the as analysed population and not the as...
  • dataset

    r37980778c78--f830f5fafab7bdb1d87d916c30c1bc00

    Slow oscillations are important for consolidation of memory during sleep, and Alzheimer’s disease (AD) patients experience memory disturbances. Thus, we examined slow...
  • dataset

    Summary of Results.

    Summary of results of follicle number counts, mRNA analyses and oxidative stress measures in ovaries of offspring born to mothers undernourished during pregnancy (UNP), during...
  • dataset

    Participant Demographics.

    1Age at enrolment,2mean value (range),3Body Mass Index,4Pre-enrolment IgA anti-tissue transglutaminase (normal range below 20 U/ml),5duration of...
  • dataset

    Baseline characteristics of the study population.

    Values are expressed as medians (range or percentage). * Hypertension: Yes = systolic blood pressure ≥140 mmHg, diastolic blood pressure ≥90 mmHg, or treated with...
  • dataset

    Experimental groups.

    Adult male and female mice used in this study were; Mc1re, recessive yellow mice, which are null mutants with a non-functional MC1R resulting in a yellow coat colour and their...
  • dataset

    Cohort characteristics.

    BMI, body mass index; IBD, inflammatory bowel disease; CD: Crohn's disease; UC: Ulcerative colitis. P25, P75: 25th and 75th percentiles; SD: standard deviation. *p<0.05 versus...
  • publication

    A Simple Analogue of Tumor-Promoting Aplysiatoxin Is an Antineoplastic Agent ...

    Protein kinase C (PKC) is widely recognized as a therapeutic target in intractable diseases such as cancer, Alzheimer’s disease (AD), and acquired immune deficiency syndrome...
  • publication

    dedup_wf_001--52d323398de494c75c4c5b7809b9bd98

    Poster presented at 'Alzheimer's Association International Conference (AAIC)'; 16th-20th July 2017; London, UK.
  • dataset

    r37980778c78--7caf43ab2fd233a383c46cb5d2e266a4

    The unfolded protein response (UPR) in the endoplasmic reticulum (ER) and the cytoplasmic heat stress response are two major stress response systems necessary for maintaining...
  • dataset

    Summary statistics.

    Values are presented as Mean ±SEM. Abbreviations: fWHR [34]; EME [44]; ULh, LLh and Nw [33]; Index 1 [47], Index 2 [48], [50], Index 3 [10], [49], ProcDist [54], [79], DiscSco1...
  • dataset

    Patient demographics.

    a Healthcare-associated infections were defined as (i) index positive blood culture collected ≥48hrs after hospital admission, and no signs or symptoms of the infection noted at...
  • dataset

    Characteristics of 20 included studies (studies are sorted by year and month ...

    Characteristics of 20 included studies (studies are sorted by year and month of publication).
  • dataset

    Study characteristics.

    *other than SAA: MAA or not reported degree of severity. †other than first-line MRD: second-line HSCT, first-line mismatched related HSCT, first-line- unrelated HSCT.‡Fouladi...
  • dataset

    Subgroup analysis.

    MPVT: main portal vein thrombosis; PVBT: portal vein branch thrombosis; TEM: extrahepatic metastasis; PVT: portal vein thrombosis.
  • dataset

    BDNF levels of different point times and antidepressant treatment.

    BDNF levels of different point times and antidepressant treatment.
  • dataset

    Characteristics of included studies.

    RCT: Randomised controlled trial. GS: Gilead Sciences. R: Roche. GSK: GlaxoSmithKline. NS: not stated. aCopies/mL converted to IU/mL by dividing by 5.bThe limit of detection of...