46 items found

Types: other Groups: figshare Open Access Tags: Genetics Medicine

Filter Results
  • other

    Data quality and feasibility of the Experience Sampling Method across the spe...

    Abstract Background Due to a number of methodological advantages and theoretical considerations, more and more studies in clinical psychology research employ the Experience...
  • other

    The impact of MTHFR 677C → T risk knowledge on changes in folate intake: find...

    © 2016 The Author(s). Open Access: This article is distributed under the terms of the Creative Commons Attribution 4.0 International License...
  • other

    Peripheral neuropathy in metachromatic leukodystrophy: Current status and fut...

    Abstract Metachromatic leukodystrophy (MLD) is an autosomal recessively inherited metabolic disease characterized by deficient activity of the lysosomal enzyme arylsulfatase A....
  • other

    Development of an infant feeding core outcome set for childhood obesity inter...

    Abstract Background Childhood obesity is a significant public health challenge that affects approximately one in five children worldwide. Infant feeding practices are implicated...
  • other

    Influence of genetic variants on toxicity to anti-tubercular agents: a system...

    MR is supported partly by Liverpool Reviews and Implementation Group (LRiG), based on funding from the National Institute for Health Research Health Technology Assessment...
  • other

    The gradient test and its finite sample size properties in a conditional maxi...

    In asymptotic theory, the gradient test proposed by Terrell is a recent likelihood-based hypothesis testing approach which can be considered as an alternative to the...
  • other

    Two subphenotypes of septic acute kidney injury are associated with different...

    Abstract Background The pathophysiology of septic acute kidney injury is inadequately understood. Recently, subphenotypes for...
  • other

    Self-monitoring of health data by patients with a chronic disease: does disea...

    Background: There is a growing emphasis on self-monitoring applications that allow patients to measure their own physical health parameters. A prerequisite for achieving...
  • other

    Cord blood DNA methylation reflects cord blood C-reactive protein levels but ...

    Abstract Background Prenatal inflammation has been proposed as an important mediating factor in several adverse pregnancy outcomes. C-reactive protein (CRP) is an inflammatory...
  • other

    Specificity versus redundancy in the RAP2.4 transcription factor family of Ar...

    Abstract Background The Arabidopsis ERFIb / RAP2.4 transcription factor family consists of eight members with highly conserved DNA binding domains. Selected members have been...
  • other

    Scaling up strategies of the chronic respiratory disease programme of the Eur...

    Abstract Action Plan B3 of the European Innovation Partnership on Active and Healthy Ageing (EIP on AHA) focuses on the integrated care of chronic diseases. Area 5 (Care...
  • other

    Assessment of fatigability in patients with spinal muscular atrophy: developm...

    Background: Fatigability has emerged as an important dimension of physical impairment in patients with Spinal Muscular Atrophy (SMA). At present reliable and valid outcome...
  • other

    An inventory of collaborative medication reviews for older adults - evolution...

    Abstract Background Collaborative medication review (CMR) practices for older adults are evolving in many countries. Development has been under way in Finland for over a...
  • other

    Surviving critical illness, what is next?: an expert consensus statement on p...

    Abstract Background The study objective was to obtain consensus on physical therapy (PT) in the rehabilitation of critical illness survivors after hospital discharge. Research...
  • other

    Qualitative study exploring the phenomenon of multiple electronic prescribing...

    BACKGROUND: A previous census of electronic prescribing (EP) systems in England showed that more than half of hospitals with EP reported more than one EP system within the same...
  • other

    Crowdsourced direct-to-consumer genomic analysis of a family quartet

    Abstract Background We describe the pioneering experience of a Spanish family pursuing the goal of understanding their own personal genetic data to the fullest possible extent...
  • other

    PROX1 and β-catenin are prognostic markers in pancreatic ductal adenocarcinoma

    Abstract Background The Wnt/β-catenin pathway has a key role in regulating cellular processes and its aberrant signaling can lead...
  • other

    Role of goblet cell protein CLCA1 in murine DSS colitis

    Abstract Background The secreted goblet cell protein CLCA1 (chloride channel regulator, calcium-activated-1) is, in addition to its established role in epithelial chloride...
  • other

    Untapped potential of multicenter studies: a review of cardiovascular risk pr...

    Abstract Background Clinical prediction models are often constructed using multicenter databases. Such a data structure poses additional challenges for statistical analysis...
  • other

    Pharmacological pain relief and fear of childbirth in low risk women; seconda...

    Abstract Background Fear of childbirth may reduce the womens’ pain tolerance during labour and may have impact on the mother-infant interaction. We aimed to assess (1) the...