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Immune responses upon Campylobacter jejuni infection of secondary abiotic mic...
Abstract Background Campylobacter jejuni infections are of rising importance worldwide. Given that innate immune receptors including nucleotide-oligomerization-domain-2 (Nod2)... -
Transient detectable viremia and the risk of viral rebound in patients from t...
Abstract Background Temporary increases in plasma HIV RNA ('blips') are common in HIV patients on combination antiretroviral therapy (cART). Blips above 500 copies/mL have been... -
dedup_wf_001--39c2dd95fe4025379e9d8a43a1fbbcaf
Manipulation of the microbiome is an emerging approach to promote health. We conducted a Phase Ia safety study of a single bladder instillation of probiotics in asymptomatic... -
Acute ileitis facilitates infection with multidrug resistant Pseudomonas aeru...
Abstract Background The rising incidence of multidrug resistant (MDR) Gram-negative bacteria including Pseudomonas aeruginosa has become a serious issue in prevention of its... -
Occurrence of marked sepsis-induced immunosuppression in pediatric septic sho...
Abstract Background While the process of sepsis-induced immunosuppression is now well described in adults, very little information is available on immune functions in pediatric... -
The cost of influenza-associated hospitalizations and outpatient visits in Kenya
Background: We estimated the cost-per-episode and the annual economic burden associated with influenza in Kenya. Methods: From July 2013–August 2014, we recruited patients with... -
Potential impact of multiple interventions on HIV incidence in a hyperendemic...
Abstract Background Multiple prevention interventions, including early antiretroviral therapy initiation, may reduce HIV incidence in hyperendemic settings. Our aim was to... -
Efficacy of imidacloprid 10%/moxidectin 1% spot-on formulation (Advocate®) in...
Abstract Background In three randomized, controlled laboratory efficacy studies, the efficacy in the prevention of patent infections of a topical combination of imidacloprid... -
Seroprevalence and risk factors of recent infection with hepatitis E virus du...
Abstract Background From September 2016–April 2017, Am Timan, Chad, experienced a large HEV outbreak in an urban setting with a limited impact in terms of morbidity and... -
Frequency and impact of confounding by indication and healthy vaccinee bias i...
Background: Evidence on influenza vaccine effectiveness (VE) is commonly derived from observational studies. However, these studies are prone to confounding by indication and... -
Post-traumatic osteomyelitis in Middle East war-wounded civilians: resistance...
Abstract Background War-wounded civilians in Middle East countries are at risk of post-traumatic osteomyelitis (PTO). We aimed to describe and compare the bacterial etiology and... -
Carvacrol ameliorates acute campylobacteriosis in a clinical murine infection...
Abstract Background The prevalence of human infections with the zoonotic pathogen Campylobacter jejuni is rising worldwide. Therefore, the identification of compounds with...
