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Ambiguity of non-systematic chemical identifiers within and between small-mol...
Background A wide range of chemical compound databases are currently available for pharmaceutical research. To retrieve compound information, including structures, researchers... -
Bioalerts: a python library for the derivation of structural alerts from bioa...
Background Assessing compound toxicity at early stages of the drug discovery process is a crucial task to dismiss drug candidates likely to fail in clinical trials. Screening... -
Studying grant decision-making: a linguistic analysis of review reports
Peer and panel review are the dominant forms of grant decision-making, despite its serious weaknesses as shown by many studies. This paper contributes to the understanding of... -
Who Believes in the Storybook Image of the Scientist?
ABSTRACT Do lay people and scientists themselves recognize that scientists are human and therefore prone to human fallibilities such as error, bias, and even dishonesty? In a... -
Leveraging 3D chemical similarity, target and phenotypic data in the identifi...
Background Drug-target identification is crucial to discover novel applications for existing drugs and provide more insights about mechanisms of biological actions, such as... -
Badapple: promiscuity patterns from noisy evidence.
Background Bioassay data analysis continues to be an essential, routine, yet challenging task in modern drug discovery and chemical biology research. The challenge is to infer... -
The growth process of higher education institutions and public policies
This paper investigates the growth over time of the size of higher education institutions (HEIs), as measured by the number of academic staff, and its association with HEI and...
