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HCV screening in a cohort of HIV infected and uninfected homeless and margina...
Background Hepatitis C virus (HCV) screening has taken on new importance as a result of updated guidelines and new curative therapies. Relatively few studies have assessed HCV... -
New tools to analyze overlapping coding regions
Background Retroviruses transcribe messenger RNA for the overlapping Gag and Gag-Pol polyproteins, by using a programmed -1 ribosomal frameshift which requires a slippery... -
A Synthesis of Hepatitis C prevalence estimates in Sub-Saharan Africa: 2000–2013
Background Hepatitis C (HCV) is a deleterious virus that can be cured with new, highly effective anti-viral treatments, yet more than 185 million individuals worldwide remain... -
Modeling HIV-HCV coinfection epidemiology in the direct-acting antiviral era:...
Background HCV treatment uptake has drastically increased in HIV-HCV coinfected patients in France since direct-acting antiviral (DAA) treatment approval, resulting in HCV cure... -
Hepatitis C virus core or NS3/4A protein expression preconditions hepatocytes...
Objectives: The occurrence of oxidative stress and endoplasmic reticulum (ER) stress in hepatitis C virus (HCV) infection has been demonstrated and play an important role in... -
Twin epidemics of new and prevalent hepatitis C infections in Canada: BC Hepa...
Background: We characterized the twin epidemics of new and prevalent hepatitis C virus (HCV) infections in British Columbia, Canada to inform prevention, care... -
Safety engineered injection devices for intramuscular, subcutaneous and intra...
Background Occupational sharps injuries are associated with transmission of bloodborne viruses to healthcare workers, including hepatitis B virus (HBV), hepatitis C virus (HCV),...