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dedup_wf_001--87621acd46c5aab91ef3cbb037f951a7
Background Growing evidence suggests that second-generation cryoballoon ablation (2G-CB) is effective in patients with persistent atrial fibrillation (PerAF). The cornerstone... -
Evidence for a Time-Invariant Phase Variable in Human Ankle Control
Human locomotion is a rhythmic task in which patterns of muscle activity are modulated by state-dependent feedback to accommodate perturbations. Two popular theories have been... -
Diving-flight aerodynamics of a peregrine falcon (Falco peregrinus)
This study investigates the aerodynamics of the falcon Falco peregrinus while diving. During a dive peregrines can reach velocities of more than 320 km h−1. Unfortunately, in... -
Pharmacological characterization of potent and selective NaV1.7 inhibitors en...
Identification of voltage-gated sodium channel NaV1.7 inhibitors for chronic pain therapeutic development is an area of vigorous pursuit. In an effort to identify more potent... -
A typology of community and stakeholder engagement based on documented exampl...
Background Despite broad consensus on the importance of community and stakeholder engagement (CSE) for guiding the development, regulation, field testing, and deployment of... -
Light-induced gene expression with photocaged IPTG for induction profiling in...
Background Inducible expression systems are frequently used for the production of heterologous proteins. Achieving maximum product concentrations requires induction profiling,... -
Functional inclusion bodies produced in the yeast Pichia pastoris
Background Bacterial inclusion bodies (IBs) are non-toxic protein aggregates commonly produced in recombinant bacteria. They are formed by a mixture of highly stable... -
Easy to use and reliable technique for online dissolved oxygen tension measur...
Background Despite the progressive miniaturization of bioreactors for screening purposes, shake flasks are still widespread in biotechnological laboratories and industry as... -
Modification of targets related to the Entner–Doudoroff/pentose phosphate pat...
Background In engineered strains of Escherichia coli, bioconversion efficiency is determined by not only metabolic flux but also the turnover efficiency of relevant pathways.... -
Engineering Saccharomyces cerevisiae with the deletion of endogenous glucosid...
Background Glycosylation of flavonoids is a promising approach to improve the pharmacokinetic properties and biological activities of flavonoids. Recently, many efforts such as... -
Systematic review and meta-analysis comparing Adjustable Transobturator Male ...
BACKGROUND AND PURPOSE: Urinary incontinence is one of the most serious complications of prostate cancer treatment. The objective of this study was to assess efficacy and safety... -
Ten simple rules for helping newcomers become contributors to open projects.
To survive and thrive, a community must attract new members, retain them, and help them be productive [1]. As openness becomes the norm in research, software development, and... -
Haves and have nots must find a better way: The case for open scientific hard...
With the current rapid spread of COVID-19, global health systems are increasingly overburdened by the sheer number of people that need diagnosis, isolation and treatment.... -
Provenance and risk in transfer of biological materials
Whereas biological materials were once transferred freely, there has been a marked shift in the formalisation of exchanges involving these materials, primarily through the use... -
A Gateway MultiSite Recombination Cloning Toolkit
The generation of DNA constructs is often a rate-limiting step in conducting biological experiments. Recombination cloning of single DNA fragments using the Gateway system... -
False positive results of Bowie and Dick type test used for hospital steam st...
Objective To determine if the standardized B&D type test for hospital steam sterilizer is correctly indicating cycle failures in slower come-up ramps cycles. Methods... -
Identification of molecular determinants that govern distinct STIM2 activatio...
The endoplasmic reticulum (ER) Ca2+ sensors stromal interaction molecule 1 (STIM1) and STIM2, which connect ER Ca2+ depletion with extracellular Ca2+ influx, are crucial for the... -
Developing a set of strong intronic promoters for robust metabolic engineerin...
Background Red yeast species in the Rhodotorula/Rhodosporidium genus are outstanding producers of triacylglyceride and cell biomass. Metabolic engineering is expected to further... -
Control of Caenorhabditis elegans germ-line stem-cell cycling speed meets req...
Background Stem cells are thought to play a critical role in minimizing the accumulation of mutations, but it is not clear which strategies they follow to fulfill that... -
Harvesting prevascularized smooth muscle cell sheets from common polystyrene ...
Cell sheet engineering has recently emerged as a promising strategy for scaffold-free tissue engineering. However, the primary method of harvesting cell sheets using...
