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Cilostazol induced migraine does not respond to sumatriptan in a double blind...
Background Cilostazol is an inhibitor of phosphodiesterase 3 and thus causes accumulation of cAMP. It induces migraine-like attacks in migraine patients. Whether the cilostazol... -
Sphenopalatine ganglion stimulation for cluster headache, results from a larg...
Background Cluster headache (CH) is a disabling primary headache disorder characterized by severe periorbital pain. A subset of patients does not respond to established... -
HbA1c levels in non-diabetic older adults - No J-shaped associations with pri...
Source: doi: 10.1186/s12916-016-0570-1 Background:To determine the shape of the associations of HbA1c with mortality and cardiovascular outcomes in non-diabetic individuals and... -
Researchers’ attitudes to the 3Rs—An upturned hierarchy?
Animal use in biomedical research is generally justified by its potential benefits to the health of humans, or other animals, or the environment. However, ethical acceptability...