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Oxidative stress and premature senescence in corneal endothelium following pe...
Abstract Background The purpose of this study was to address the question of how the premature senescence process may affect corneal endothelium after penetrating keratoplasty,... -
Incidence and impact on outcomes of acute kidney injury after a stroke: a sys...
Abstract Background Patients with chronic kidney disease have worse outcomes after stroke. However, the burden of acute kidney injury after stroke has not been extensively... -
An analysis of SPECT/CT non-visualization of sentinel lymph nodes in renal tu...
Abstract Background Sentinel lymph node biopsy (SLNB) after intratumoral injection of 99mTc labeled nanocolloid and imaging with scintigraphy and SPECT/CT in renal tumors is... -
Bone marrow failure may be caused by chromosome anomalies exerting effects on...
Abstract Background The majority of the cases of bone marrow failure syndromes/aplastic anaemias (BMFS/AA) are non-hereditary and considered idiopathic (80â 85%). The... -
New-onset non-infectious pulmonary manifestations among patients with systemi...
Abstract Objective The objective was to estimate the incidence of lung disease among patients with systemic lupus erythematosus (SLE). Methods Using Swedish register data, we... -
Comparative effectiveness of primary tumor resection in patients with stage I...
Abstract Background Previous studies comparing primary tumor resection (PTR) to palliative treatment for advanced-stage pancreatic ductal adenocarcinoma (PDA) were limited by... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Comparison of efficacy and safety of drug-eluting versus uncoated balloon ang...
Abstract Background This quantitative meta-analysis was conducted to evaluate the efficacy and safety of drug-eluting balloon (DEB) vs. uncoated balloon (UCB) in patients with... -
Prevalence and in-hospital outcomes of diabetes among patients with acute cor...
Abstract Background Guidelines have classified patients with acute coronary syndrome (ACS) and diabetes as a special population, with specific sections presented for the... -
Lower urinary tract symptoms in men: challenges to early hospital presentatio...
Abstract Background The point at which men seek medical care for lower urinary tract symptoms (LUTS) varies between individuals. Presentation to hospital with complications... -
Morbidity burden of respiratory diseases attributable to ambient temperature:...
Abstract Background There are significant associations between ambient temperature and respiratory disease mortality. However, few studies have assessed the morbidity burdens of... -
Dimethyl fumarate attenuates reactive microglia and long-term memory deficits...
Abstract Background Systemic inflammation is associated with increased cognitive decline and risk for Alzheimer’s disease. Microglia (MG) activated during systemic inflammation... -
Association between E469K polymorphism in the ICAM1 gene and the risk of diab...
Abstract Background Inflammation may be a key pathophysiological mechanism in diabetic nephropathy (DN). Intercellular adhesion molecule 1 (ICAM1) is an acute phase marker of... -
Temporal trends of dialysis requiring acute kidney injury after orthotopic ca...
Abstract Background The epidemiology and outcomes of acute kidney injury (AKI) in prevalent non-renal solid organ transplant recipients is unknown. Methods We assessed the... -
iNOS is not responsible for RyR1 S-nitrosylation in mdx mice with truncated d...
Abstract Background Previous research indicated that nitric oxide synthase (NOS) is the key molecule for S-nitrosylation of ryanodine receptor 1 (RyR1) in DMD model mice (mdx... -
Pilot non dialysis chronic renal insufficiency study (P-ND-CRIS): a pilot stu...
Abstract Background Before establishing a prospective cohort, an initial pilot study is recommended. However, there are no precise guidelines on this subject. This paper reports... -
Long-term survival and prognostic factors for locally advanced renal cell car...
Abstract Background Previous related studies have mainly focused on renal cell carcinoma (RCC) with venous tumor thrombus, specifically inferior vena cava tumor thrombus with... -
Selection of reliable reference genes for the normalisation of gene expressio...
Abstract Background Macrophages are key players in the initiation, perpetuation and regulation of both innate and adaptive immune responses. They largely perform these roles... -
The face of Ebola: changing frequency of haemorrhage in the West African comp...
Abstract Background The West-African (WA) Zaire Ebolavirus disease (EVD) outbreak was characterized by an exceptionally high number of cases and deaths as compared with the... -
Avelumab in patients with previously treated metastatic melanoma: phase 1b re...
Abstract Background We report phase 1b data from patients enrolled in the JAVELIN Solid Tumor clinical trial (NCT01772004) with unresectable stage IIIC or IV melanoma that had...
