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Erythropoietin as an add-on treatment for cognitive side effects of electroco...
Abstract Background Electroconvulsive therapy (ECT) is the most effective treatment for severe depression, but its use is impeded by its cognitive side effects. Novel treatments... -
Pleural effusion from intrathoracic migration of a ventriculo-peritoneal shun...
Abstract Background Pleural effusion is a rare complication of ventriculo-peritoneal (VP) cerebrospinal fluid (CSF) shunting and its diagnosis is difficult in patients with... -
Comparative analyses of the in vivo induction and transmission of α-synuclein...
Abstract α-synuclein (αS) is the major component of several types of brain pathological inclusions that define neurodegenerative diseases termed synucleinopathies. Central... -
Periostin involved in the activated hepatic stellate cells-induced progressio...
Abstract Background Incomplete thermal ablation may induce invasiveness of hepatocellular carcinoma (HCC). Here, we investigated whether activated hepatic stellate cells (HSCs)... -
Highly active promoters and native secretion signals for protein production d...
Abstract Background The filamentous ascomycete Aspergillus niger is used in many industrial processes for the production of enzymes and organic acids by batch and fed-batch... -
Prevention of multiple system atrophy using human bone marrow-derived mesench...
Abstract Background Multiple system atrophy (MSA) is a sporadic neurodegenerative disorder of unknown etiology, but is closely associated with damage to dopaminergic neurons.... -
Factors influencing decision regret regarding placement of a PEG among substi...
Abstract Background A tube feeding decision aid designed at the Ottawa Health Research Institute was specifically created for substitute decision-makers who must decide whether... -
The decline of FGM in Egypt since 1987: a cohort analysis of the Egypt Demogr...
Abstract Background Female genital mutilation (FGM) has been a longstanding tradition in Egypt and until recently the practice was quasi-universal. Nevertheless, there are... -
Novel three-dimensional bone ‘mapping’ software can help assess progression o...
Abstract Imaging of bone metastasis response to therapy is a research priority. Stradwin is a new software-tool, with demonstrated sub-voxel accuracy in assessing cortical bone... -
Aberrant activation of NF-κB signaling in mammary epithelium leads to abnorma...
Abstract Background Approximately 1 in 5 women diagnosed with breast cancer are considered to have in situ disease, most often termed ductal carcinoma in situ (DCIS). Though... -
Plasma sTNFR1 and IL8 for prognostic enrichment in sepsis trials: a prospecti...
Abstract Background Enrichment strategies improve therapeutic targeting and trial efficiency, but enrichment factors for sepsis trials are lacking. We determined whether... -
Hemodynamic impacts of flow diverter devices on the ophthalmic artery
Abstract Background Flow diverter devices are increasingly used for endovascular treatment of internal carotid artery aneurysms. Treatment of ophthalmic segment aneurysms with... -
Comparison of clinical features, management and outcomes of osteosarcoma loca...
Abstract Background The aim of this study was to compare proximal fibular and proximal tibial sites regarding osteosarcoma in the proximal crus. Furthermore, we proposed a... -
Mechanical ventilation strategies for intensive care unit patients without ac...
Abstract Background It has been shown that the application of a lung-protective mechanical ventilation strategy can improve the prognosis of patients with acute lung injury... -
Association of adipokines with blood pressure, arterial elasticity and cardia...
Abstract Background Adipokines are a set of cytokines secreted by white adipose tissue that have been suggested to be involved in the development of cardiovascular diseases. We... -
The association between socioeconomic status and visual impairments among pri...
Abstract Background Glaucoma is one of the most leading causes of permanent visual impairments in Korea, and social expenses spent for the glaucoma are increasing. This study is... -
Untargeted metabolomics reveals the effect of lovastatin on steroid-induced n...
Abstract Purpose Lovastatin is an important medicine and it shows a significant effect against glucocorticoid-induced necrosis of the femoral head. This study aimed to... -
Reduced expression of miR-146a in human bronchial epithelial cells alters neu...
Abstract Background The role of miRNAs in the pathogenesis and determining the phenotypes of asthma is not fully elucidated. miR-146a has been previously shown to suppress... -
Optical coherence tomography findings after longitudinal ablation for an unde...
Abstract Background Heavy coronary artery calcification is responsible for stent underexpansion, which is associated with increased in-stent restenosis. Here we report a case in... -
11β-HSD1 plays a critical role in trabecular bone loss associated with system...
Abstract Background Despite their efficacy in the treatment of chronic inflammation, the prolonged application of therapeutic glucocorticoids (GCs) is limited by significant...