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Genetic tool for fate mapping of Oct4 (Pou5f1)-expressing cells and their pro...
Abstract Background Methods based on site-specific recombinases are widely used in studying gene activities in vivo and in vitro. In these studies, constitutively active or... -
Developmental and morphological studies in Japanese medaka with ultra-high re...
We propose ultra-high resolution optical coherence tomography to study the morphological development of internal organs in medaka fish in the post-embryonic stages at micrometer... -
Synthesis of graphene oxide-quaternary ammonium nanocomposite with synergisti...
Abstract Background Bacterial infection is one of the most common complications in burn, trauma, and chronic refractory wounds and is an impediment to healing. The frequent... -
Quantitative evaluation of corneal epithelial edema after cataract surgery us...
Abstract Purpose The optical density of the cornea can be evaluated quantitatively by “densitometry” using a rotating Scheimpflug camera. Densitometry allows evaluation of... -
Impact of faculty development programme on self-efficacy, competency and atti...
Abstract Background Soon after Bhutan’s first medical university was established in 2012, Faculty Development Programmes (FDPs) were adopted for efficient delivery of... -
Influence of volatile anesthesia versus total intravenous anesthesia on chron...
Abstract Background Many patients develop chronic postsurgical pain (CPSP) after cardiac surgery, which interferes with their sleep, mood, and quality of life. Studies have... -
A novel transcription factor specifically regulates GH11 xylanase genes in Tr...
Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the... -
Aberrant activation of NF-κB signaling in mammary epithelium leads to abnorma...
Abstract Background Approximately 1 in 5 women diagnosed with breast cancer are considered to have in situ disease, most often termed ductal carcinoma in situ (DCIS). Though... -
Frailty in end-stage renal disease: comparing patient, caregiver, and clinici...
Abstract Background Frailty is associated with poor outcomes for patients on dialysis and is traditionally measured using tools that assess physical impairment. Alternate... -
Construction of a trifunctional cellulase and expression in Saccharomyces cer...
Abstract Background Cellulose is the most important component of lignocellulose, and its degradation requires three different types of enzymes to act synergistically. There have... -
High-frequency ultrasound of the skin in systemic sclerosis: an exploratory s...
Abstract Background Thickened skin is a major clinical feature in patients with systemic sclerosis (SSc). We investigated changes of skin thickness in patients with SSc using... -
OCT proves that vitreomacular adhesion is significantly more likely to develo...
Abstract Background SD-OCT is becoming commonplace in everyday practice. Vitreomacular adhesions (VMAs) are being more routinely diagnosed. Predictive studies to the natural... -
Multiphoton in vivo imaging with a femtosecond semiconductor disk laser
We use an ultrafast diode-pumped semiconductor disk laser (SDL) to demonstrate several applications in multiphoton microscopy. The ultrafast SDL is based on an optically pumped... -
Diffraction pattern study for cell type identification
This paper presents our study regarding diffracted intensity distribution in Fresnel and Fraunhofer approximation from different cell types. Starting from experimental... -
RIP3 dependent NLRP3 inflammasome activation is implicated in acute lung inju...
Abstract Background NLRP3 inflammasome is involved in the inflammatory responses during acute lung injury (ALI). RIP3 triggered NLRP3 inflammasome activation independent of... -
The effect of a rapid molecular blood test on the use of antibiotics for noso...
Abstract Background Appropriate use of antimicrobials is essential to improve outcomes in sepsis. The aim of this study was to determine whether the use of a rapid molecular... -
Identification of a putative methyltransferase gene of Babesia bigemina as a ...
Abstract Background Bovine babesiosis is caused by apicomplexan pathogens of the genus Babesia such as B. bigemina and B. bovis. These tick-borne pathogens have a complex... -
Association between periodontitis and peripheral artery disease: a systematic...
Abstract Background Inflammation is a common feature of both peripheral arterial disease (PAD) and periodontitis. Some studies have evaluated the association between PAD and... -
A systematic review of the clinical application of data-driven population seg...
Abstract Background Data-driven population segmentation analysis utilizes data analytics to divide a heterogeneous population into parsimonious and relatively homogenous groups... -
High-Quality draft genome sequence of the Lotus spp. microsymbiont Mesorhizob...
Abstract Mesorhizobium loti strain CJ3Sym was isolated in 1998 following transfer of the integrative and conjugative element ICEMlSymR7A, also known as the R7A symbiosis island,...
