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Genetic tool for fate mapping of Oct4 (Pou5f1)-expressing cells and their pro...
Abstract Background Methods based on site-specific recombinases are widely used in studying gene activities in vivo and in vitro. In these studies, constitutively active or... -
Synthesis of graphene oxide-quaternary ammonium nanocomposite with synergisti...
Abstract Background Bacterial infection is one of the most common complications in burn, trauma, and chronic refractory wounds and is an impediment to healing. The frequent... -
A novel transcription factor specifically regulates GH11 xylanase genes in Tr...
Abstract Background The filamentous fungus Trichoderma reesei is widely utilized in industry for cellulase production, but its xylanase activity must be improved to enhance the... -
RIP3 dependent NLRP3 inflammasome activation is implicated in acute lung inju...
Abstract Background NLRP3 inflammasome is involved in the inflammatory responses during acute lung injury (ALI). RIP3 triggered NLRP3 inflammasome activation independent of... -
Identification of a putative methyltransferase gene of Babesia bigemina as a ...
Abstract Background Bovine babesiosis is caused by apicomplexan pathogens of the genus Babesia such as B. bigemina and B. bovis. These tick-borne pathogens have a complex... -
Point-of-care ultrasound curriculum for internal medicine residents: what do ...
Abstract Background Point-of-care Ultrasound is a relative new diagnostic tool for internists. Since 2019, it is a mandatory skill for internal medicine residents in the... -
Chromosomal integration vectors allowing flexible expression of foreign genes...
Abstract Background Campylobacter jejuni is a major cause of human gastroenteritis yet there is limited knowledge of how disease is caused. Molecular genetic approaches are... -
Transcriptome analysis reveals regional and temporal differences in mucosal i...
Abstract Background Postnatal development of the mammalian mucosal immune system is crucial for responding to the rapid colonization by commensal bacteria and possible exposure... -
High shear stress suppresses proliferation and migration but promotes apoptos...
Abstract Background Early neointimal hyperplasia of vein graft may be ameliorated via enhancing intravenous surface shear stress. Cellular processes including proliferation,... -
The Effect of Everolimus on Scar Formation in Glaucoma Filtering Surgery in a...
Purpose: To investigate the efficiency of everolimus on the prevention of postoperative scar in a rabbit model of glaucoma filtering surgery in comparison with mitomycin-C... -
Overexpression of MALT1-A20-NF-κB in adult B-cell acute lymphoblastic leukemia
Abstract Background A20 is a dual inhibitor of NF-κB activation and apoptosis in the tumor necrosis factor receptor 1 signaling pathway, and both are related to tumorigenesis.... -
Kinetic, kinematic, magnetic resonance and owner evaluation of dogs before an...
Abstract Background The amputation of a limb is a surgical procedure that is regularly performed in small animal practice. In spite of several clinical reports indicating high... -
Development of a 3D printed device to support long term intestinal culture as...
Abstract Background Most interactions between pathogenic microorganisms and their target host occur on mucosal surfaces of internal organs such as the intestine. In vitro organ... -
Tyrosinase inhibitory activity of flavonoids from Artocarpus heterophyllous
Abstract Background Tyrosinase is an oxidoreductase that is very important in medicine and cosmetics because the excessive production of melanin causes hyperpigmentation. The... -
Overexpression of Contactin 1 promotes growth, migration and invasion in Hs57...
Abstract Background Contactin1 (CNTN1) has been shown to play an important role in the invasion and metastasis of several tumors; however, the role of CNTN1 in breast cancer has... -
Improved co-registration of ex-vivo and in-vivo cardiovascular magnetic reson...
Abstract Background Ex-vivo cardiovascular magnetic resonance (CMR) imaging has played an important role in the validation of in-vivo CMR characterization of pathological... -
Intraoperative changes in whole-blood viscosity in patients undergoing robot-...
Abstract Background The aim of this study was to investigate the effect of the steep Trendelenburg position (STP) with pneumoperitoneum on whole-blood viscosity (WBV) in... -
Tracheid cell-wall structures and locations of (1 → 4)-β-d-galactans and (1 →...
Abstract Background Compression wood (CW) forms on the underside of tilted stems of coniferous gymnosperms and opposite wood (OW) on the upperside. The tracheid walls of these... -
Notch1 regulates tongue cancer cells proliferation, apoptosis and invasion
Objectives: Notch1 regulates tumor biology in a complex, context-dependent manner. The roles of Notch1 in tongue cancer are still controversial. The aim of this study is to... -
An advanced bioinformatics approach for analyzing RNA-seq data reveals sigma ...
Abstract Background Alternative σ factors are important transcriptional regulators in bacteria. While σB has been shown to control a large regulon and play important roles in...
