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Retrospective analysis in oculocutaneous albinism patients for the 2.7 kb del...
Abstract Background Oculocutaneous albinism (OCA) is an autosomal recessive disorder. A significant portion of OCA patients has been found with a single pathogenic variant... -
The magnitude of antibiotic resistance to Helicobacter pylori in Africa and i...
Abstract Background Worldwide Helicobacter pylori (H.pylori) treatment is of great challenge due to increased antibiotic resistance. The burden of H. pylori antibiotic... -
Prevalence and antibiotic resistance of bacteria isolated from the cerebrospi...
Abstract Background Postoperative central nervous system infections (PCNSIs) represent a serious complication, and the timely use of antibiotics guided by the identification of... -
Acanthamoeba containing endosymbiotic chlamydia isolated from hospital enviro...
Abstract Background Environmental chlamydiae belonging to the Parachlamydiaceae are obligate intracellular bacteria that infect Acanthamoeba, a free-living amoeba, and are a... -
Central nervous system manganese induced lesions and clinical consequences in...
Abstract Background Around 47–74% of patients with hereditary hemorrhagic telangiectasia (HHT) have hepatic vascular malformations (HVMs); magnetic resonance images (MRI) of the... -
Bacterial etiology of sputum from tuberculosis suspected patients and antibio...
Abstract Objective The current study aims to explore the bacteriology of sputum of tuberculosis (TB) suspected patients. A cross-sectional study was carried out in the sputum... -
Ubiquitous giants: a plethora of giant viruses found in Brazil and Antarctica
Abstract Background Since the discovery of giant viruses infecting amoebae in 2003, many dogmas of virology have been revised and the search for these viruses has been... -
Single-photon emission computed tomography/computed tomography imaging of RAG...
Abstract Background Expression of the Receptor for Advanced Glycation Endproducts (RAGE) initiates pro-inflammatory pathways resulting in lung destruction. We hypothesized that... -
iCAGES: integrated CAncer GEnome Score for comprehensively prioritizing drive...
Abstract Cancer results from the acquisition of somatic driver mutations. Several computational tools can predict driver genes from population-scale genomic data, but tools for... -
Mass spectrometry-based identification and whole-genome characterisation of t...
Abstract Background The pteropine orthoreovirus (PRV) was isolated from monkey (Macaca fascicularis) faecal samples collected from human-inhabited areas in Lopburi Province,... -
First detection and genetic characterization of canine Kobuvirus in domestic ...
Abstract Background Canine Kobuvirus (CaKoV) has been detected both in healthy and diarrheic dogs and in asymptomatic wild carnivores. In this study, we conducted a survey of... -
Nationwide epidemiologic study of norovirus-related hospitalization among Jap...
Abstract Background Older adults are vulnerable to hospitalization or death from norovirus infection, but the actual disease burden remains unknown. Therefore, we conducted a... -
Genetic and epidemiological analysis of norovirus from children with gastroen...
Abstract Background Norovirus is a leading cause of viral gastroenteritis worldwide with a peak of disease seen in children. The epidemiological analysis regarding the virus... -
The impact of diagnostic microbiology on de-escalation of antimicrobial thera...
Abstract Background Minimising antimicrobial overuse is needed to limit antimicrobial resistance. There is little evidence on how often microbiological testing informs... -
Is 1H-MR spectroscopy useful as a diagnostic aid in MSA-C?
Abstract Background Multiple system atrophy (MSA) is a sporadic adult-onset neurodegenerative disease with a cerebellar subtype where ataxic symptoms predominate (MSA-C)... -
Advanced non-cardia gastric cancer and Helicobacter pylori infection in Vietnam
Abstract Background The incidence of gastric cancer in the Northern city, Hanoi is higher than in the Southern city, Ho Chi Minh, Vietnam. We previously reported that... -
Performance of a brief geriatric evaluation compared to a comprehensive geria...
Abstract Background Geriatric syndromes are rarely detected in family medicine. Within the AGE program (active geriatric evaluation), a brief assessment tool (BAT) designed for... -
Prevalence and pattern of antibiotic resistance of Staphylococcus aureus isol...
Abstract Background Studies have implicated Staphylococcus aureus as the leading cause of septicemia in the Tamale metropolis of Ghana. The aim of this study was to determine... -
First cases of contagious ovine digital dermatitis in Germany
Abstract Contagious ovine digital dermatitis (CODD) is a significant disease of the ovine foot characterised by severe lameness and progressive separation of the hoof horn... -
Diversity of antibiotics in hospital and municipal wastewaters and receiving ...
Abstract Background Antibiotics are extensively discharged into the environment through sewages. These emergent contaminants cause health and environmental risks by toxicity,...